Neurobiology

Paperback | May 1, 1994

byGordon M. Shepherd

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This widely used and highly praised textbook has been extensively revised to reflect the most exciting research across the entire range of neuroscience. A new feature is an introductory discussion of the mechanisms of gene regulation, while the superfamily of molecules responsible formembrane signaling is given new emphasis as a unifying theme throughout molecular and cellular neurobiology. The roles of these molecules in impulse conduction and synaptic transmission are fully explained, and illustrated by computer models. For the first time in a neurobiology text, thesemechanisms can be explored by using a state-of-the-art interactive computer program provided with an accompanying tutorial handbook. In the sections dealing with neural systems, the comparative approach continues to be used to illustrate general principles. Students learn about the progress beingmade toward a molecular basis for sensory perception and new methods for revealing the neural activity underlying sensory and motor functions are described. There is an emphasis on the plasticity of both sensory and the motor circuits in mediating functions that reflect the effects of activity orrecovery from injury. Central systems continue to be featured as the culmination of neural evolution. These include the systems vital for all animals, such as sleeping, feeding and reproduction, as well as the systems for language, emotion and higher cognitive functions that reach their peak inhumans. There is special emphasis on recent work on memory, contrasting the mechanisms for short-term working memory and long-term memory and summarizing the present understanding of the mechanisms of long-term potential. The twin themes of organizational levels and comparative systems help bringtogether the vast range of studies and provides a conceptual framework that unifies the field of neurobiology. As in previous editions, the text continues to draw on the advantages of having a single author. In addition, leaders in a number of specialties have assisted the author, so that the textrepresents the most up-to-date views of current research on the nervous system.

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This widely used and highly praised textbook has been extensively revised to reflect the most exciting research across the entire range of neuroscience. A new feature is an introductory discussion of the mechanisms of gene regulation, while the superfamily of molecules responsible formembrane signaling is given new emphasis as a unify...

Gordon M. Shepherd is Professor of Neuroscience at Yale University. He is the author of The Synaptic Organization of the Brain (Oxford University Press, 1979).

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Format:PaperbackDimensions:784 pages, 10 × 7 × 0.68 inPublished:May 1, 1994Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195088433

ISBN - 13:9780195088434

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Table of Contents

1. IntroductionPART I: Molecular and Cellular Mechanisms2. Molecular Neurobiology3. Neurons and Glia4. The Membrane Potential5. The Action Potential6. The Synapse7. Synaptic Potentials and Synaptic Integration8. Second Messengers and Neuromodulators9. Developmental NeurobiologyPART II: Sensory Systems10. Introduction: From Receptors to Perceptions11. Chemical Senses12. The Somatic Senses13. Muscle Sense and Kinesthesia14. The sense of Balance15. Hearing16. VisionPART III: Motor Systems17. Introduction: The Nature of Motor Function18. Autonomic Functions19. Reflexes and Fixed Motor Responses20. Locomotion21. Motor Hierarchies22. Manipulation23. Communication and SpeechPART IV: Central Systems24. Introduction: The Nature of Central Systems25. Biorhythms26. Visceral Brains: Feeding27. Visceral Brains: Mating28. Emotion29. Learning and Memory30. The Cerebral Cortex and Human Behavior

Editorial Reviews

"Although there has been an explosive increase in factual information about the nervous system in the past decade, an integrated conceptual approach to understanding its workings has been sorely lacking, especially in introductory textbooks. This handsome book is the most lucid andcomprehensive available to fill this void." --New England Journal of Medicine