Neurodegeneration in Multiple Sclerosis

byM. FilippiEditorM. Rovaris, G. Comi

Hardcover | August 6, 2007

Neurodegeneration in Multiple Sclerosis by M. Filippi
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In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and for monitoring the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy of cMRI to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is changing dramatically our understanding of how MS causes irreversible disability. In detail, there is an increasing body of MR evidence that MS is not only a white matter disease and does not only cause focal lesions, as well as that neurodegeneration is an important aspect of the disease (since the earliest clinical phases), which is only partially related to inflammatory changes. There is also increasing perception that modern MR methodologies should be more extensively employed in clinical trials to derive innovative information.

Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it will bi and indispensable tool for all those working in this field.

Dr. Massimo Filippi was born in 1961, took his Graduation in Medicine in 1986 and his Post-Degree Graduation in Neurology in 1990. His research activity has always been focussed on the use of MR-based technology to improve our understanding of how neurological diseases determine progressive accumulation of irreversible physical disabil...
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Title:Neurodegeneration in Multiple SclerosisFormat:HardcoverProduct dimensions:236 pages, 9.25 X 6.1 X 0 inShipping dimensions:236 pages, 9.25 X 6.1 X 0 inPublished:August 6, 2007Publisher:Springer NatureLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:8847003903

ISBN - 13:9788847003903

Appropriate for ages: All ages

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