Neuroglia in the Aging Brain by Jean De VellisNeuroglia in the Aging Brain by Jean De Vellis

Neuroglia in the Aging Brain

EditorJean De Vellis

Paperback | November 19, 2010

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A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.
Title:Neuroglia in the Aging BrainFormat:PaperbackDimensions:526 pagesPublished:November 19, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617370886

ISBN - 13:9781617370885

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Table of Contents

Part I. Cellular and Molecular Changes of Aged and Reactive AstrocytesNeuromorphological Changes in Neuronal and Neuroglial Populations of the Cerebral Cortex in the Aging Rat: Neurochemical CorrelationsMaria Angeles Peinado, Manuel Martinez, Maria Jesus Ramirez, Adoracion Quesada, Juan Angel Pedrosa, Concepcion Iribar, and Jose Maria PeinadoDiversity in Reactive AstrocytesSudarshan K. Malhotra and Theodor K. ShnitkaAstrocytic Reaction After Traumatic Brain InjuryJesús Boya, J. L. Calvo, Angel López-Carbonell, and José E. García-MauriñoPart II. Neuron-Glia IntercommunicationAstrocytes In Situ Exhibit Functional Neurotransmitter ReceptorsMarilee K. Shelton and Ken D. McCarthyGlia and Extracellular Space Diffusion Parameters in the Injured and Aging BrainEva SykováIntercellular Diffusional Coupling between Glial Cells in Slices from the StriatumBrigitte Hamon, Jacques Glowinski, and Christian GiaumeGlial Cell Involvement in Brain Repair and the Effects of AgingElizabeth A. Howes and Peter J. S. SmithATP Signaling in Schwann CellsThierry Amédée, Aurore Colomar, and Jonathan A. ColesPart III. Neurotrophins, Growth Factors, and Neurohormones in Aging and RegenerationGliosis Growth Factors in the Adult and Aging Rat BrainGérard Labourdette and Françoise EclancherRole of Fibroblast Growth Factor-2 in AstrogliosisJohn F. ReillyTrophins as Mediators of Astrocyte Effects in the Aging and Regenerating BrainJudith Lackland and Cheryl F. DreyfusResponses in the Basal Forebrain Cholinergic System to AgingZezong Gu and J. Regino Perez-PoloEffects of Estrogens and Thyroid Hormone on Development and Aging of Astrocytes and OligodendrocytesKevin Higashigawa, Alisa Seo, Nayan Sheth, Giorgios Tsianos, Hogan Shy, Latha Malaiyandi, and Paola S. TimirasPart IV. Metabolic ChangesNeurotoxic Injury and AstrocytesMichael Aschner and Richard M. LoPachinAmmonium Ion Transport in Astrocytes: Functional ImplicationsNeville BrookesPart V. Astrocytes and the Blood-Brain Barrier in AgingMolecular Anatomy of the Blood-Brain Barrier in Development and AgingDorothee Krause, Pedro M. Faustmann, and Rolf DermietzelThe Blood-Brain Barrier in the Aging BrainGesa Rascher and Hartwig WolburgAstrocytes and Barrier-provided Microvasculature in the Developing BrainLuisa RoncaliPart VI. Astrocytes in Neurodegenerative DiseasesMicroglial and Astrocytic Reactions in Alzheimer's DiseaseDouglas G. Walker and Thomas G. BeachActivated Neuroglia in Alzheimer's DiseaseKurt R. Brunden and Robert C. A. FredericksonReactive Astroglia in the Ataxic Form of Creutzfeldt-Jakob Disease: Cytology and Organization in the Cerebellar CortexMiguel Lafarga, Nuria T. Villagra, and Maria T. BercianoIschemic Injury, Astrocytes, and the Aging BrainRobert FernGlial-Neuronal Interactions during Oxidative Stress: Implications for Parkinson's DiseaseCatherine MytilineouAstrocytic Changes Associated with Epileptic SeizuresAngélique Bordey and Harald SontheimerSynaptic and Neuroglial Pathobiology in Acute and Chronic Neurological DisordersLee J. MartinAstrocytes and Ammonia in Hepatic EncephalopathyMichael D. Norenberg

Editorial Reviews

Foreword by Paola S. Timiras, md, phd, University of California at Berkeley, Berkeley, CA Overall, this carefully edited book organized its contents with a shrewd mind to bring out importance of glial cell function in the CNS vis-a-vis its functional unit, the neurons...This book with helpful diagrams and illustrations, and with excellent coverage of literature is not only useful for the beginners in neuroscience, but is an excellent reference material for gerontologists and researchers in neurological disorders. - Journal of Chemical Neuroanatomy