Neuroimmune Pharmacology

Hardcover | May 29, 2008

EditorTsuneya Ikezu, Howard Gendelman

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The chapters contained in this volume show scientific relationships among historically separated fields. This allows a unique opportunity for scientists and students to gain broad knowledge in disparate fields of clinical medicine and biomedical research. Overall, the text integrates cutting-edge neuroscience, immunology, pharmacology, neurogenetics, neurogenesis, gene therapy, adjuvant therapy, proteomics, and magnetic resonance imaging. It is a rich harvest and readers will gain a perspective that has not been readily available. Exposure to such a wealth of ideas is bound to inspire readers to undertake new and productive research initiatives. In summary, this is a volume not to be put on the shelf as a reference, but to be read cover to cover by aspiring neuroscientists.Dr. Patrick L. McGeer Professor Emeritus Kinsmen Laboratory of Neurological Research, University of British ColumbiaThis exciting new textbook, Neuroimmune Pharmacology, reflects the history and vision of the Society on NeuroImmune Pharmacology and of the Societyâ?Ts official publication, the Journal of Neuroimmune Pharmacology. All three represent deliberations arising from a relatively young, interdisciplinary, and dynamic field of research, which have major translational implications for neurodegenerative, neuroinflammatory, neuropsychiatric diseases, and infections of the nervous system. They all demonstrate the synergistic value of integrating the parts: Neuroscience, Immunology, and Pharmacology. The extraordinary accomplishment of Neuroimmune Pharmacology is its comprehensive nature. It will be enthusiastically welcomed by members of the Society and will serve as the definitive resource for all students and researchers interested in various topics that are so well covered in the book.Dr. Phillip K. PetersonPresident, Society on NeuroImmune PharmacologyProfessor, Department of Medicine, University of MinnesotaWritten for: Graduate students, postdoctoral fellows, health care providers, researchers, scientists and physicians who are interested in basic and clinical aspects of how the immune system affects neurodegenerative diseases. Primary disciplines are Immunology, Neuroscience, and Pharmacology

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From the Publisher

 The chapters contained in this volume show scientific relationships among historically separated fields. This allows a unique opportunity for scientists and students to gain broad knowledge in disparate fields of clinical medicine and biomedical research. Overall, the text integrates cutting-edge neuroscience, immunology, pharmacology...

From the Jacket

The chapters contained in this volume show scientific relationships among historically separated fields. This allows a unique opportunity for scientists and students to gain broad knowledge in disparate fields of clinical medicine and biomedical research. Overall, the text integrates cutting-edge neuroscience, immunology, pharmacology,...

Tsuneya Ikezu, M.D., Ph.D. Associate Professor, Department of Pharmacology and Experimental Neuroscience Associate Director, Center for Neurovirology and Neurodegenerative Disorders Description: Dr. Ikezu was born in Tokyo, Japan, obtained MD-PhD (Clinical Pharmacology in Major) from University of Tokyo School of Medicine, and had p...
Format:HardcoverDimensions:878 pages, 10.98 × 8.27 × 0 inPublished:May 29, 2008Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0387725725

ISBN - 13:9780387725727

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Table of Contents

Preface.- Acknowledgments.- Abbreviations.- Introducing Neuroimmune Pharmacology Howard E. Gendelman and Tsuneya Ikezu.- SECTION 1: Immunology of the Nervous System.- Innate and Adaptive Immunity in Health and Disease Howard E. Gendelman and Eliezer Masliah.- Anatomical Networks: Structure and Function of the Nervous System Eliezer Masliah.- The Blood Brain Barrier William A. Banks.- Anterior Chamber and Retina Leila Kump and Eyal Margalit.- Hippocampus and Memory Huangui Xiong.- Glial and Neuronal Cellular Composition, Biology and Physiology Kalipada Pahan.- Astrocytes, Oligodendrocytes and Schwann Cells Malabendu Jana, Subhajit Dasgupta, Anuja Ghorpade, and Kalipada Pahan.- Macrophages, Microglia, and Dendritic Cells Anuja Ghorpade and Jonathan Kipnis.- Neuronal and Glial Signaling Murali Prakriya and Richard J. Miller.- The Vertebrate Retina Wallace B. Thoreson.- Lymphocytes and the Nervous System Larisa Y. Poluektova.- Stem Cells Hui Peng, Nicholas Whitney, Kang Tang, Myron Toews, and Jialin Zheng.- Molecular Neurobiology.-  Neurobiology and Neural Systems Tsuneya Ikezu and Howard E. Gendelman.- Cytokines and Chemokines Yunlong Huang, Nathan Erdmann, Terry D. Hexum and Jialin Zheng.- CNS Cell Signaling Ramendra N. Saha, Keshore R. Bidasee and Kalipada Pahan.- SECTION 2: Nervous System Diseases and Immunity: Clinical Descriptions Neurodegeneration Serge Przedborski.- Neuroimmunologic Diseases.- Multiple Sclerosis and Other Demyelinating Diseases Samantha Soldan, Gregory Wu, Clyde Markowitz, and Dennis L. Kolson.- Guillain-Barré, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, and Axonal Degeneration and Regeneration Ralf Gold and Klaus V. Toyka.- Guillain Barré-Syndrome Helmar C. Lehmann and Kazim A. Sheikh.- Immunological Disorders Associated with Neurologic Disease.- Autoimmune Disease M. Patricia Leuschen.- NeuroAIDS Yuri Persidsky.- HTLV-I/II Kazunori Fugo, Christian W. Grant and Steven Jacobson.- Viral Encephalitis Clinton Jones and Eric M. Scholar.- Neurodegenerative Diseases Associated with Neuroimmunologic Dysfunction.- Alzheimer's Disease Tsuneya Ikezu.- Parkinson's Disease Serge Przedborski.- Amyotrophic Lateral Sclerosis Ericka P. Simpson, Albert A. Yen and Stanley H. Appel.- Huntington's Disease Seymour Gendelman.- Prion Diseases Qingzhong Kong and Richard A. Bessen.- Glaucoma Deven Tuli and Carl B. Camras.-  Stroke and Cerebrovascular Disease Alison E. Baird.- Neurogenesis and Brain Repair G. Jean Harry.- Familial Neurodegenerative Diseases and Single Nucleotide Polymorphisms Michael Slifer and Jeffery M. Vance.- Psychiatric Disorders.- The Neuroimmune System in Psychiatric Disorders L. Charles Murrin and Mark P. Thomas.- Major Depression, Bipolar Syndromes and Schizophrenia Frederick Petty, Sriram Ramaswamy, Prasad R. Padala, Jean D. Deupree, and David B. Bylund.- Molecular Pathogenesis for Schizophrenia and Major Depression Norbert Müller and Markus J. Schwarz.- Drugs of Abuse and the Immune System Toby K. Eisenstein, David E. Kaminsky, Rahil T. Rahim, and Thomas J. Rogers.- SECTION 3: Therapeutics.- Neuropharmacology Terry D. Hexum, L. Charles Murrin and Eric M. Scholar.- Neurodegenerative Diseases Jinsy A. Andrews and Paul H. Gordon.- Multiple Sclerosis M. Patricia Leuschen, Kathleen M. Healey, Mary L. Filipi.- HIV-Associated Dementia Miguel Madariaga and Susan Swindells.- Immunotherapy Jonathan Kipnis.- Alzheimer's Disease Dave Morgan and Marcia N. Gordon.- Parkinson's Disease and Amyotrophic Lateral Sclerosis R. Lee Mosley.- Protective and Regenerative Autoimmunity in CNS Injury Jonathan Kipnis and Michal Schwartz.- Adjuvants Sam Sanderson.- Emerging Therapeutic and Diagnostics: Nanotechnology, Gene Therapy, Genomics and Proteomics, and Bioimaging.- Polymer Nanomaterials Alexander V. Kabanov and Elena V. Batrakova.- Gene Therapy and Vaccination William J. Bowers, Michelle C. Janelsins and Howard J. Federoff.- Proteomics and Genomics Wojciech Rozek and Pawel S. Ciborowski.- Neuroimaging Michael D. Boska and Matthew L. White.- Glossary.- Index.-

Editorial Reviews

"This book Neuroimmune Pharmacology edited by Drs. Ikezu and Gendelman presents a complete and comprehensive assessment of the basic concepts, current research, and cutting-edge technology regarding the disciplines of neuroscience, immunology, and pharmacology that has been assembled by more than 80 experts. It is an in-depth resource for beginners as well as for experts in the field. The text is clear and concise and includes pertinent concepts related to the pathogenesis of neurodegenerative diseases from a viewpoint of basic immunology and pharmacology.""The topics are concise, bolstered by datafrom pioneering and current research in the area, and conclude with a summary and a series of review questions. Each section leads into the next section so as to establish afoundation for the subsequent topic area to be addressed. The ordering of the sections is particularly beneficial to students just starting out in the field, allowing them to grasp the fundamental concepts of neuroanatomy, neurobiology, and neuroimmunology before applying that knowledge to specific disease states. Advanced students will also find the textbook helpful in offering a review of previously learned concepts and a multiplicity of chapters that comprehensively cover specific topics to be addressed in the later two sections." (Shilpa J. Buch & Rachel Williams, Journal of Neuroimmune Pharmacology, September, 2008)