Neuroimmunology of the Skin: Basic Science to Clinical Practice by Richard D. GransteinNeuroimmunology of the Skin: Basic Science to Clinical Practice by Richard D. Granstein

Neuroimmunology of the Skin: Basic Science to Clinical Practice

EditorRichard D. Granstein, Thomas A. Luger

Paperback | October 14, 2010

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Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system-immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.
Title:Neuroimmunology of the Skin: Basic Science to Clinical PracticeFormat:PaperbackDimensions:264 pages, 10.24 × 7.6 × 0 inPublished:October 14, 2010Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642071511

ISBN - 13:9783642071515

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Table of Contents

Introduction.- Basic Neuroimmunology of the Skin.- Neuroanatomy of the Skin.- Neuroreceptors and Mediators.- Interaction of the Neuroimmune and Vascular Systems.- Immune Circuits of the Skin.- Modulation of Immune Cells by Products of Nerves.- Regulation of Immune Cells by POMC Peptides.- Regulation of Cutaneous Immunity by Catecholamines.- The Role of Neuropeptide Endopeptidases in Cutaneous Immunity.- Toll-Like Receptors: Role in Neurobiology.- Stress in Cutaneous Immunity.- Neuroendocrine Effects of Stress.- Stress and Cutaneous Immunity.- Effects of Stress on Inflammatory Skin Disease.- Photoneuroimmunology: Modulation of the Neuroimmune System by UV-Light.- Neurophysiology of Itch.- Autonomic Effects on the Skin.- Neurobiology of Hair, Sebaceous Glands, Eccrine/Apocrine Glands.- The Nervous System and the Pathophysiology of Skin Disorders.- Psoriasis.- Atopic Dermatitis.- Alopecia Areata.- Urticaria.- Acne Vulgaris and Rosacea.- Wound Healing.- Aging.- Index.

Editorial Reviews

From the reviews:"Granstein and Luger boldly went where no one has gone before. . they have successfully compiled a book which cuts across scientific disciplines, ranging from dermatology, immunology, neurobiology and psychology. . it is a useful tool to comprehend how the psychological state - such as stress perception - triggers or aggravates skin diseases. . The book gives valuable inspiration for both, basic scientists and clinicians, and future cross-cutting research endeavours as well as their clinical translation can be envisioned to arise from reading this book." (Petra Arck, Journal der Deutschen Dermatologischen Gesellschaft, Vol. 7 (11), November, 2009)