Neuroprogression and Staging in Bipolar Disorder

Paperback | July 22, 2015

EditorFlavio Kapczinski, Eduard Vieta, Pedro V. S. Magalhaes

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After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease,clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viableaddition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging,comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field ofbipolar disorder.

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After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease,clinical course and outcome are not as benign as in...

Flavio Kapczinski is Professor of Psychiatry, Director of Research and Head of the Molecular Psychiatry Laboratory at the Hospital de Clinicas de Porto Alegre, Brazil. He is Consultant for the National Council of Scientific and Technological Development (CNPq). He has wide experience in clinical research, being lead investigator in sev...

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Format:PaperbackDimensions:368 pagesPublished:July 22, 2015Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198709994

ISBN - 13:9780198709992

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Table of Contents

Willem Nolem: Foreword1. Robert M. Post: Clinical staging in bipolar disorder: a historical perspective2. Ralph W. Kupka, Manon H. J. Hillegers and Jan Scott: Staging systems in bipolar disorder3. Iria Grande, Luis Guilherme Streb and Flavio Kapczinski: Allostatic load and accelerated aging in bipolar disorder4. Gabriel R. Fries, Pedro V. S. Magalhaes, Flavio Kapczinski and Michael Berk: Neuroprogression as the biological underpinning of staging in bipolar disorder5. Adriane R. Rosa, Clarissa S. Gama and Eduard Vieta: Functioning and illness progression in bipolar disorder6. Anabel Martinez-Aran, Caterina del Mar Bonnin, Carla Torrent, Brisa Sole, Imma Torres and Esther Jimenez: Cognition and illness progression in bipolar disorder7. Sergio A. Strejilevich and Diego J. Martino: Social cognition and staging in bipolar disorder8. Gustavo H. Vazquez and Xenia Gonda: Affective temperaments: potential latent stages of bipolar disorders9. Benicio N. Frey, Luciano Minuzzi, Bartholomeus C.M. Haarman and Roberto B. Sassi: Neuroimaging and illness progression10. Aroldo A. Dargel and Marion Leboyer: Biomarkers in illness progression in bipolar disorder11. Joana Bucker, Marcia Kauer-Sant'Anna and Lakshmi N. Yatham: Childhood adversity and illness progression in bipolar disorder12. Anusha Baskaran, Benjamin I. Goldstein and Roger McIntyre: Vascular and Metabolic Medical Comorbidities and Neuroprogression in Bipolar Disorder13. Romain Icick and Frank Bellivier: Substance misuse in staging bipolar affective disorder14. Janusz K. Rybakowski: Excellent lithium responders, resilience and staging in bipolar disorder15. Vicent Balanza-Martinez, Maria Lacruz and Rafael Tabares-Seisdedos: Staging and early intervention in bipolar disorder16. Aline Andre Rodrigues and Mauricio Kunz: Pharmacological treatment of late-stage bipolar disorder17. Maria Reinares and Francesc Colom: Illness progression and psychosocial interventions in bipolar disorder18. Flavio Kapczinski, Eduard Vieta, Pedro V. S. Magalhaes and Michael Berk: Staging systems in bipolar disorder: current findings, future directions and implications for clinical practice