Nevogenesis: Mechanisms and Clinical Implications of Nevus Development by Ashfaq A. MarghoobNevogenesis: Mechanisms and Clinical Implications of Nevus Development by Ashfaq A. Marghoob

Nevogenesis: Mechanisms and Clinical Implications of Nevus Development

EditorAshfaq A. Marghoob

Hardcover | October 13, 2012

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The "Abtropfung" theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.
Ashfaq Marghoob, MD, graduated in 1987 from the School of Medicine, State University of New York at Stony Brook, where he later performed his Residency in Dermatology. He was appointed Clinical Assistant Professor in the Department of Dermatology at Stony Brook in 1995 and Associate Professor of Dermatology in 2005. Dr. Marghoob curren...
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Title:Nevogenesis: Mechanisms and Clinical Implications of Nevus DevelopmentFormat:HardcoverDimensions:220 pages, 10 × 7.01 × 0.01 inPublished:October 13, 2012Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642283969

ISBN - 13:9783642283963

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Table of Contents

Nevogenesis: Changing Theories.- Classifying Melanocytic Nevi.- Evolution of Nevi.- The Dual Pathway of Nevogenesis.- Confocal Microscopy: Improving Our Understanding of Nevogenesis.- Nevi In Children And Adults: Dermoscopic Patterns And The Development of New Nevi .- Etiology of Congenital Melanocytic Nevi And Related Conditions.- Molecular Nevogenesis.- Nevogenesis: A Benign Metastatic Process?.- Nevus Senescence.- Gene-Environment Interactions In Nevogenesis.- Malignant Transformation of Melanocytic Nevi.- Disappearance of Melanocytic Nevi.