New Concepts of Antiviral Therapy by Elke BognerNew Concepts of Antiviral Therapy by Elke Bogner

New Concepts of Antiviral Therapy

EditorElke Bogner, Andreas Holzenburg

Paperback | October 29, 2010

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Antiviral drugs are vital - but imperfect - tools for treatment and prevention of viral infections. Undesirable effects, from drug resistant viruses to low oral bioavailability, toxicity and severe side effects limit clinical usefulness. These factors drive demand for improved antiviral strategies. This book offers an up-to-date review of new drugs and targets, novel modes of action, vector-based treatments and even the blocking of defined genes by inhibiting mRNA formation (siRNA). Includes contributions by acknowledged experts; the book will serve as a compendium for R&D and educational professionals, and be of value for students.
Title:New Concepts of Antiviral TherapyFormat:PaperbackDimensions:558 pagesPublished:October 29, 2010Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1441940499

ISBN - 13:9781441940490

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Table of Contents

ContentsPart 1. Concepts of therapy for RNA viruses Therapeutic vaccination in chronic hepadnavirus infection by Michael Rogendorf and Mengji LuCharacterization of targets for antiviral therapy of Flaviridae infections by Peter BorowskiInhibition of Hepatitis C virus by nucleic acid-based antiviral approaches by Michael Frese and Ralf BartenschlagerInhibitors for respiratory viruses by Ernst Kuechler and Joachim SeipeltAnti-viral approaches against influenza viruses by Stephan Pleschka, Stephan Ludwig, Thorsten Wolff and Oliver PlanzA new approach to an Influenza virus live vaccine: Modification of the cleavage site of the haemagglutine by reverse genetics by Jürgen Stech, Holger Garn and Hans-Dieter KlenkNew concepts in anti-HIV therapies by Justin Stebbing, Mark Bower and Brian GazzardEvaluation of current strategies to inhibit HIV entry, integration and maturation by Jaqueline D. Reeves, Stephen D. Barr and Stephan PöhlmannManaging antiretroviral resistance by Barbara Schmidt, Monika Tschoschner, Hauke Walter and Klaus KornPart 2. Concepts of therapy for DNA virusesSelective inhibitors of the replication of poxviruses by Johan Neyts and Erik de ClercqMaribavir: A promising new antiherpes therapeutic Agent by Karen K. BironBenzimidazle-D-ribonucleosides as antiviral agents that target HCMV terminase by John C. Drach, Leroy B. Townsend and Elke BognerRecent developments in anti-herpesviral therapy based on protein kinase inhibitors by Thomas Herget and Manfred MarschallImmune therapy against papillomavirus-related tumors in humans by Lutz GissmannPart 3. Concepts of therapy for emerging virusesThe SARS Corona virus receptor ACE-2 A potential target for antiviral therapy by Jens H. Kuhn, Sheli R. Radoshitzky, Wenhui Li, Swee Kee Wong, Hyeryun Choe and Michael FarzanTherapy of Ebola and Marburg virus infections by Mike BrayPart 4. General concepts of therapyProteasome inhibitors as complementary or alternative antiviral therapeutics by Susanna Prösch and Marion KaspariHuman monoclonal antibodies for prophylaxis and therapy of viral infections by Jan ter Meulen and Jaap GoudsmitVector-based antiviral therapy by Armin Ensser Index