Non-Motor Symptoms of Parkinsons Disease

Hardcover | November 17, 2014

EditorK. Ray Chaudhuri, Eduardo Tolosa, Anthony H. V. Schapira

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Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have beenextensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians.The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require researchinto novel (non-dopaminergic) drug therapies for the future.Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.

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From the Publisher

Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have beenextensively researched, and effective clinical to...

K. Ray Chaudhuri is Head and Co-Medical Director at the National Restless Legs Syndrome Clinic and National Parkinson Foundation Center of Excellence, Kings College Hospital, Ruskin Wing, Denmark Hill, London, UK. Eduardo Tolosa is Professor of Neurology and Director of Parkinson Disease and Movement Disorder at the University of Barce...

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Format:HardcoverDimensions:512 pages, 9.69 × 6.73 × 0.1 inPublished:November 17, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199684243

ISBN - 13:9780199684243

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Table of Contents

Section 1: NMS: General concepts1. K. Ray Chaudhuri and Niall Quinn: What are the non-motor symptoms of Parkinson's disease?2. David A. Gallagher and Anthony H. V. Schapira: Non-motor symptoms and pre-motor diagnosis of Parkinson's disease3. Eduardo Tolosa, Carles Gaig, Joan Santamaria and Yaroslau Compta: Non-motor symptoms in the early motor stages of Parkinson's disease4. Miguel Coelho, Joaquim J Ferreira: Non-motor symptoms in advanced Parkinson's disease5. Pablo Martinez-Martin, Carmen Rodriguez-Blazquez, Maria Joao Forjaz: Assessment tools for non-motor symptoms of Parkinson's disease in the clinical setting6. David J. Brooks and Nicola Pavese: Imaging non-motor aspects of Parkinson's disease7. Meike Kasten and Christine Klein: Non-motor signs in genetic forms of Parkinson's diseaseSection 2: Specific NMS of PD8. Daisy L. Whitehead and Richard. G. Brown: Cognitive dysfunction of Parkinson's disease9. David A. Gallagher and Anette Schrag: Depression, anxiety and apathy in Parkinson's disease10. David J. Burn and Alison J. Yarnall: Dementia in Parkinson's disease11. Benzi M. Kluger and Joseph H. Friedman: Fatigue in Parkinson's disease12. Christopher G. Goetz, Nico J. Diederich and Gilles Fenelon: Psychosis in Parkinson's disease13. Lynn Marie Trotti and David B. Rye: Neurobiology of sleep: The role of dopamine in Parkinson's disease related sleep disorders14. Alex Iranzo and Eduard Tolosa: REM sleep behaviour disorder in Parkinson's disease15. William G. Ondo: Parkinson's disease and restless legs syndrome16. Birgit Frauscher and Werner Poewe: Excessive daytime sleepiness in Parkinson's disease17. Ryuji Sakakibara and Clare Fowler: Bladder dysfunction in Parkinson's disease18. Orna Moore, Gila Bronner, Sharon Hassin-Baer and Nir Giladi: Sexuality in Parkinson's disease19. Fabrizio Stocchi and Margherita Torti: Gastrointestinal dysfunctions in Parkinson's disease20. Italo Biaggioni and Horacio Kaufmann: Postural hypotension in Parkinson's disease21. Julia Johnson , Marian L. Evatt and K. Ray Chaudhuri: Sialorrhoea in Parkinson's disease22. Heinz Reichmann and Birgit Herting: Olfaction in Parkinson's disease23. Santiago Perez-Lloret, Estelle Dellapina, Jean Pelleprat, Maria Veronica Rey, Christine Brefel-Courbon and Olivier Rascol: Chronic pain and Parkinson's disease24. T. Baba, I. Estrada-Bellmann, E. Mori and A. Takeda: Visual function in Parkinson's diseaseSection 3: Quality of Life, Comorbidity, drug effects and surgery25. Pablo Martinez-Martin, Francisco J. Carod Artal and Jesus de Pedro Cuesta: Non-motor symptoms and health-related quality of life: an overview26. Graeme J. A. Macphee and Douglas G. MacMahon: Non motor symptoms and co-morbidity in Parkinson's disease27. Shen-Yang Lim, Elena Moro, Ai Huey Tan and Anthony E. Lang: Non-motor symptoms of Parkinson's disease and the effects of deep brain stimulation surgery28. Regina Katzenschlager and Andrew Evans: Impulse dyscontrol and dopamine dysregulation syndrome29. Vincent Ries, J. Carsten Moller, Marcus M. Unger and Wolfgang H. Oertel: Treatment-related non-motor symptoms in Parkinson's disease30. Giovanni Mostile and Joseph Jankovic: Thermoregulatory dysfunction in Parkinson's disease31. Reddy P, Antonini A and Odin P: The role of continuous dopaminergic stimulation in the management of non-motor symptoms in Parkinson's disease

Editorial Reviews

Review from previous edition: "...this is a valuable reminder that there are many non-motor symptoms that can be just as distressing." --BMA Medical Book Competition 2010