Nuclear Medicine: Practical Physics, Artifacts, and Pitfalls

Paperback | December 25, 2014

byDaniel A. Pryma

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In contrast to most anatomic radiographic imaging techniques, nuclear medicine permits real time, non-invasive imaging of human physiology and pathophysiology and also allows for exquisite targeting of disease with therapeutic radiology. To open this window to the processes of human disease,one must first understand the physical processes behind radioactive decay and emission, as well the principles of radiation detection. Practical Nuclear Medicine Physics provides residents and practitioners in nuclear medicine and radiology a readable explanation of the physics concepts underpinningnuclear imaging and how they impact the utilization and interpretation of those images. Following a brief introductory section, the book provides numerous case examples, illustrating various imaging artifacts and pitfalls that can be recognized and remedied with a solid understanding of the physics behind the procedure. Understanding and applying the physics behind nuclear medicine isessential to maximizing not only diagnostic and therapeutic accuracy for providing optimal patient care, but "Practical Physics" is a required portion of radiology residency education and a designated area of the board exams.

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In contrast to most anatomic radiographic imaging techniques, nuclear medicine permits real time, non-invasive imaging of human physiology and pathophysiology and also allows for exquisite targeting of disease with therapeutic radiology. To open this window to the processes of human disease,one must first understand the physical proces...

Daniel a. Pryma is Assistant Professor of Radiology; Modality Chief, Nuclear Medicine/Molecular Imaging at the University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Format:PaperbackDimensions:208 pages, 9.25 × 7.5 × 0.68 inPublished:December 25, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199918031

ISBN - 13:9780199918034

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Table of Contents

1. Introduction to Nuclear Medicine2. RadiationX-raysNuclear nomenclatureNuclear radiationElectron captureBeta emissionPositron EmissionAlpha EmissionIsomeric transitionGamma radiationInternal conversionAuger electronsUnits of radioactivity3. RadiobiologyUnits of radiation exposureDeterministic effectsStochastic effectsRadiation safety4. Radiation detectors - ionization detectorsIonization chambersDose calibratorsSurvey metersProportional counters5. Radiation detectors - single photonCollimatorsScintillatorsPhotomultiplier tubesThe gamma cameraStatic planar imagingDynamic imagingGated imagingSPECTSPECT/CTGamma probes and well counters6. Radiation detection - PETPET principlesPET acquisition and reconstructionTime of flightPET/CTPET/MR7. Dose calibrator artifactsCase 1. AltitudeCase 2. GeometryCase 3. Materials8. Gamma camera artifactsCase 1. Cracked crystalCase 2. Hygroscopic crystalCase 3. PMT malfunctionCase 4. Flood nonuniformity9. Planar acquisition artifactsCase 1. Off peak acquisitionCase 2. Motion artifactCase 3. Dose infiltrationCase 4. Collimator penetration10. SPECT acquisition artifactsCase 1. Center of rotation errorCase 2. Filtered back projection streakCase 3. Noisy imagesCase 4. Iterative reconstruction errorsCase 5. Motion artifact11. PET acquisition artifactsCase 1. PMT malfunctionCase 2. Crystal temperature instabilityCase 3. Table misregistrationCase 4. Scatter correction errorsCase 5. Attenuation correction errorsCase 6. CT artifacts affecting PET reconstruction12. Dose calibrator pitfallsCase 1. Dose calibrator contaminationCase 2. Wrong setting used on dose calibratorCase 3. High background activity13. Single photon pitfallsCase 1. ProsthesesCase 2. Recent prior studyCase 3. ContaminationCase 4. Poor dynamic timingCase 5. Background activity14. PET pitfallsCase 1. InfiltrationCase 2. Treatment effect mimics new diseaseCase 3. Misregistration and attenuation correctionCase 4. Respiratory motion artifact15. Therapy pitfallsCase 1. Empiric dosing exceeds safe limitsCase 2. GI toxicityCase 3. Radioactive vomitCase 4. Therapy infusion via indwelling catheter16. Puzzlers