Oligomerization in Health and Disease

Other | May 7, 2013

byJesus Giraldo, Jesus Giraldo, Francisco Ciruela

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This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

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From the Publisher

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.Contributions from leading authoritiesInforms and updates on all the latest developments in the field

Format:OtherDimensions:656 pages, 1 × 1 × 1 inPublished:May 7, 2013Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123869501

ISBN - 13:9780123869500

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Table of Contents

Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization

  1. Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization
  2. Structural, Evolutionary and Assembly Principles of Protein Oligomerization
  3. Physico-Chemical Principles of Protein Aggregation
  4. Structural Aspects of Amyloid Formation
  5. Section II. Oligomerization in Seven-Transmembrane Receptors

  6. Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers
  7. Challenges in the Development of Heteromer-GPCR-Based Drugs
  8. Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"
  9. G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
  10. Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of Abuse
  11. Section III. Oligomerization in Ion Channels

  12. Social Networking among Voltage-Gated Potassium Channels
  13. Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy
  14. Consequences of Dimerization of the Voltage Gated Proton Channel
  15. Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate Receptors
  16. Section IV. Oligomerization in Enzymes

  17. The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase
  18. Oligomerization of Dynamin Superfamily Proteins in Health and Disease
  19. Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications
  20. Oligomerization in Endoplasmic Reticulum Stress Signaling
  21. Section V. Oligomerization in Regulatory Proteins

  22. Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity
  23. Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease
  24. Chemokine Oligomerization in Cell Signaling and Migration
  25. Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking