Optical Imaging of Brain Function and Metabolism by Ulrich DirnaglOptical Imaging of Brain Function and Metabolism by Ulrich Dirnagl

Optical Imaging of Brain Function and Metabolism

EditorUlrich Dirnagl, K.M. Einhäupl, Arno Villringer

Paperback | May 31, 2013

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. . . . . At last the doctor will be freed from the tedious interpretation of screens and photographs. Instead, he will examine and scan through his patient directly. Wearing optical-shutter spectacles and aiming a pulsed laser torch, he will be able to peer at the beating heart, study the movement of a joint or the flexing of a muscle, press on suspect areas to see how the organs beneath respond, check that pills have been correctly swallowed or that an implant is savely in place, and so on. A patient wearing white cotton or nylon clothes that scatter but hardly absorb light, may not even have to undress . . . . .. David Jones, Nature (1990) 348:290 Optical imaging of the brain is a rapidly growing field of heterogenous techniques that has attracted considerable interest recently due to a number of theoretical advantages in comparison with other brain imaging modalities: it uses non­ ionizing radiation, offers high spatial and temporal resolution, and supplies new types of metabolic and functional information. From a practical standpoint it is important that bedside examinations seem feasible and that the implementations will be considerably less expensive compared with competing techniques. In October 1991, a symposium was held at the Eibsee near Garmisch, Germany to bring together the leading scientists in this new field.
Title:Optical Imaging of Brain Function and MetabolismFormat:PaperbackPublished:May 31, 2013Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1489924701

ISBN - 13:9781489924704


Table of Contents

Near Infrared Spectroscopy of the Brain.- NMR and time-resolved optical studies of brain imaging.- Wavelength dependence of the differential pathlength factor and the log slope in time-resolved tissue spectroscopy.- Towards human brain near infrared imaging: Time resolved and unresolved spectroscopy during hypoxic hypoxia.- Measurement of human hypothermic cerebral oxygen metabolism by transmission spectroscopy.- Optical CT imaging of hemoglobin oxygen-saturation using dual-wavelength time gate technique.- Optical properties of normal human intracranial tissues in the spectral range of 400 to 2500 nm.- Imaging of Brain Function Using Intrinsic Signals.- Optical imaging of the functional architecture in cat visual cortex: The layout of direction and orientation domains.- Mapping of neural activity patterns using intrinsic optical signals: From isolated brain preparations to the intact human brain.- Fiber optic imaging of subcortical neural tissue in freely behaving animals.- Olfactory information processing in insects revealed by real-time optical imaging of intrinsic signals.- Thermal Imaging of the Brain.- Infrared imaging of brain function.- IR thermal imaging of a monkey's head: Local temperature changes in response to somatosensory stimulation.- Optical Measurement of Ion Concentrations in Brain Cells and Tissues.- Spatiotemporal inhomogeneity of [Ca]i in neurons.- Intracellular ion concentrations in the brain: approaches towards in situ confocal imaging.- Optical Access to the Brain Microcirculation.- Optical access to the brain: how artificial are cranial window techniques?.- Multiparametric imaging of microregional circulation over the brain cortex by videoreflectometry.- Towards imaging of cerebral blood flow and metabolism on a microscopical scale in vivo.- Emerging Optical Techniques.- Detection of brain free oxygen radical generated photons in vivo: Preliminary results.- Diffusion properties of brain tissue measured with electrode methods and prospects for optical analysis.- Measuring oxygen using oxygen dependent quenching of phosphorescence: A status report.- Laser fluorescence spectroscopic experiments for monitoring molecules in brain.- Infrared-interference videomicroscopy of living brain slices.- Non-Optical Reference Techniques.- Blood-brain barrier transport measurements using PET-scanning and intravenous double indicator technique.- Nuclear magnetic resonance studies of human brain in vivo: Anatomy, function, and metabolism.- Autoradiographic and biochemical imaging in cerebral ischemia.- Contributors.