Organic Synthesis by Christine L. WillisOrganic Synthesis by Christine L. Willis

Organic Synthesis

byChristine L. Willis, Martin Wills

Paperback | July 1, 1995

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The ability to design effective syntheses is an essential skill for organic chemists. This valuable text uses a wide range of examples to teach students of chemistry how to adopt a logical and versatile approach to the design of synthetic routes. The concept of retrosynthetic analysis - ameans for identifying simple starting materials for a synthesis - is first introduced with emphasis on the importance of bond polarity and functional group interconversions. The next section describes how an effective route to a target molecule containing more than one functional group can beelucidated, and gives useful strategies to adopt when designing syntheses. Later chapters review methods for the control of chemo-, regio-, and stereoselectivity, and include a discussion of protecting groups. Finally, four syntheses of the pyrrolidine alkaloids are compared and contrasted usingthe principles described in the book. Practice examples are provided throughout, making this concise text an invaluable study aid for all undergraduate chemists.
Chris Willis and Martin Wills are both at the University of Bath.
Title:Organic SynthesisFormat:PaperbackDimensions:96 pages, 9.69 × 7.44 × 0.24 inPublished:July 1, 1995Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0198557914

ISBN - 13:9780198557913


Table of Contents

1. Introduction to synthesis2. Retrosynthetic analysis I: The basic concepts3. Retrosynthetic analysis II: Latent polarity and FGIs4. Retrosynthetic analysis III: Strategy and planning in synthesis5. Selectivity I: Chemoselectivity and protecting groups6. Chemoselectivity II: Regioselectivity7. Chemoselectivity III: Stereoselectivity8. Selected organic synthesisGlossaryAppendix: Synthon table

From Our Editors

This series of short texts provides accessible accounts of a range of essential topics in chemistry. Written with the needs of the student in mind, the Oxford Chemistry Primers offer just the right level of detail for undergraduate study, and will be invaluable as a source of material commonly presented in lecture courses yet not adequately covered in existing texts. All the basic principles and facts in a particular area are presented in a clear and straightforward style, to produce concise yet comprehensive accounts of topics covered in both core and specialist courses. This book introduces a logical approach for the design of synthetic routes to reasonably complex organic molecules from simple starting materials. It describes the concept of 'retrosynthesis', which allows suitable simple starting materials to be identified; the importance of bond polarity and functional group interconversions; how to find an effective route to a target molecule containing more than one functional group; and valuable strategies to adopt when designing syntheses. The text also inc

Editorial Reviews

`A gentle introduction to the subject'Peter Budd, University of Manchester, New Scientist, March 1997