Organophosphorus Reagents: A Practical Approach in Chemistry

Hardcover | July 22, 2004

EditorPatrick J. Murphy

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Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way oflife. Its chemistry plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in theessential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation ofIminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry,but also for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods.

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Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way oflife. Its chemistry plays a key role in the ...

Dr Patrick J Murphy is currently a senior lecturer in Organic Chemistry at the University of Wales, Bangor. His research interests include organo-phosphorus chemistry, guanidine chemistry and natural product synthesis

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Format:HardcoverDimensions:289 pages, 9.21 × 6.14 × 0.82 inPublished:July 22, 2004Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198502621

ISBN - 13:9780198502623

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Table of Contents

1. Dr P.J. Murphy: Introduction to "Organophosphorus Chemistry"2. Professor Jonathan Williams and Matthew Clarke: The synthesis and applications of Phosphines3. Dr R. Alan Aitken and Nazira Karodia: Applications of phosphorus (III) and (V) compounds as reagents in synthesis4. Dr Andrew Abell and Dr Michael Edmonds: The Wittig and related Reactions5. Dr Ranier Schobert: Applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds6. Dr I O'Neil and Dr J.M. Southern: Preparation and reactions of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction7. Dr Matthew D. Fletcher: Phospho-Transfer processes leading to (P-C) bond formation8. Dr Sven Asmus, Dr Uwe Bergstrasser, Dr Heinrich Heydt, Dr Marion Schmitz and Professor Manfred Regitz: Low-coordinated phosphorus compounds9. Dr David M. Williams and Dr Vicki H. Harris: Phosphorus methods in nucleotide chemistry