Origin and Evolution of New Gene Functions by Manyuan LongOrigin and Evolution of New Gene Functions by Manyuan Long

Origin and Evolution of New Gene Functions

byManyuan Long

Paperback | September 14, 2012

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This is the first book addressing origin and evolution of new gene functions. Although interest in evolutionary novelties can be traced back to the time of Darwin, the appreciation and systematical experimental pursuit of the origin and evolution of new gene functions did not appear until the early years of the last decade. Sixteen chapters from pioneers and leading scientists in this newly emerging field provide overviews of how new genes with novel functions originated and evolved. Broad issues related to new gene evolution are analyzed, ranging from molecular mechanisms to population genetics to theoretical conjecture of the minimum building blocks for protein diversity. Both insightful reviews and new original results of theoretical and experimental analyses were presented, which are valuable for researchers and students in further pursuit of the fascinating field of new gene evolution.
Title:Origin and Evolution of New Gene FunctionsFormat:PaperbackDimensions:199 pagesPublished:September 14, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401039828

ISBN - 13:9789401039826

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Table of Contents

Preface; M. Long. 1. The contribution of RNAs and retroposition to evolutionary novelties; J. Brosius. 2. The emergence of a synthetic theory of intron evolution; S.J. De Souza. 3. Introns in gene evolution; L. Fedorova, A. Fedorov. 4. Functional divergence in protein (family) sequence evolution; Xun Gu. 5. The EBG system of E. coli: Origin and evolution of a novel beta-galactosidase; B.G. Hall. 6. The fucosyltransferase gene family: An amazing summary of the underlying mechanisms of gene evolution; C. Javaud, F. Dupuy, A. Maftah, R. Julien, J.-M. Petit. 7. Origin of new genes: Evidence from experimental and computational analyses; M. Long, M. Deutsch, Wen Wang, E. Betran, F. Brunet, Jianming Zhang. 8. Transposable elements and vertebrate protein diversity; A. Lorenc, W. Makalowski. 9. Birth of human-specific genes during primate evolution; J.-L. Nahon. 10. Evolution by gene duplication revisited: Differentiation of regulatory elements vs proteins; T. Ohta. 11. Modular assembly of genes and the evolution of new functions; L. Patthy. 12. Origin and evolution of a new gene expressed in the Drosophila sperm axoneme; J.M. Ranz, A.R. Ponce, D.L. Hartl, D. Nurminsky. 13. Molecular mechanisms of exon shuffling: Illegitimate recombination; A.van Rijk, H. Bloemendal. 14. Recent evidence for the exon theory of genes; S.W. Roy. 15. The universe of exons revisited; S. Saxonov, W. Gilbert. 16. Population-genetic models of the fates of duplicate genes; B. Walsh.