Origin and Evolution of the Vertebrate Immune System by L. Du PasquierOrigin and Evolution of the Vertebrate Immune System by L. Du Pasquier

Origin and Evolution of the Vertebrate Immune System

EditorL. Du Pasquier, G.W. Litman

Paperback | October 4, 2011

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The book presents the most current knowledge, ideas and speculations about the origin of the adaptive immune system and its evolution. The accumulation of genetic, molecular and biological data across various classes of vertebrates and phyla within the animal kingdom has helped elucidate major elements of genetic conservation and specific variations on that theme. Several scenarios linking together genome evolution and the origin of receptors and the differentiation of lymphocyte lineage are now envisioned at a much more general and integrated level than ever before. The volume is a collection of chapters centered around the phylogeny of the immune system written by scientists who are at the forefront of research in the field. It presents a fresh mix of subjects and new approaches presented for the first time in form of reviews. Clearly not comprehensive, the book delineates the current and controversial issues in this area.
Title:Origin and Evolution of the Vertebrate Immune SystemFormat:PaperbackDimensions:336 pagesPublished:October 4, 2011Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642640788

ISBN - 13:9783642640780


Table of Contents

Bridge to Invertebrates.- New Approaches Towards an Understanding of Deuterostome Immunity.- The Antimocrobial Host Defense of Drosophila.- Origin and Evolution of the Complement System.- Genome Paralogy.- Phylogeny of Lower Vertebrates and Their Immunological Structures.- Recombination-Activating Genes, Transposition, and the Lymphoid-Specific Combinatorial Immune System: A Common Evolutionary Connection.- Transcription Factor Expression in Lymphocyte Development.- The Phylogenetic Origin of Antigen-Specific Receptors.- Immunoglobulin Isotypes: Structure, Function, and Genetics.- Evolution of Vertebrate Immunoglobulin Variable Gene Segments.- The Immune System of Cartilaginous Fish.- Immune-Type Diversity in the Absence of Somatic Rearrangement.- Evolution and Somatic Diversification of Immunoglobulin Light Chains.- Evolution of the T Cell Receptor Signal Transduction Units.