Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton

Hardcover | April 19, 2016

byRoger Smith, Paul Wordsworth

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Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton 2e is a definitive reference providing comprehensive coverage of common polygenic and rare monogenic disorders, emphasizing new advances in bone cell biology and human skeletal disease. With an up-to-date account of common and rare metabolic disorders of the skeleton, including their causes, clinical aspects, and treatment, this book offers the reader clarity in the complex field of the molecular biology of the skeleton. Topics covered include bone biology and investigation,osteoporosis, osteomalacia and rickets, parathyroid bone disease, Paget disease, and the effects of malignancy on the skeleton. Newer metabolic bone disorders are also included, along with chapters on osteogenesis imperfecta, skeletal dysplasias, osteopetrosis and osteosclerosis, Marfan syndrome,Ehlers-Danlos syndrome, fibrous dysplasia, and ectopic mineralisation.Essential for postgraduates and clinicians, this accessible and highly illustrated book provides a clear authoritative account of metabolic bone diseases in their widest sense. Bringing together considerable advances in the field, it discusses molecular causes and personal experiences of alldisorders, ensuring a comprehensive and didactic reference.Enriched with over 100 new illustrations and revised chapters to reflect a rapidly developing field, this second edition will be indispensable for those who look after patients with metabolic bone disease, including general physicians, rheumatologists, endocrinologists, and orthopaedic surgeons,along with paediatricians and geneticists.

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Oxford Textbook of Clinical and Biochemical Disorders of the Skeleton 2e is a definitive reference providing comprehensive coverage of common polygenic and rare monogenic disorders, emphasizing new advances in bone cell biology and human skeletal disease. With an up-to-date account of common and rare metabolic disorders of the skeleton...

Roger Smith is an Honorary Consultant Physician at the Nuffield Orthopaedic Centre, Oxford. Paul Wordsworth is a Professor of Rheumatology at the University of Oxford and an Honorary Consultant Rheumatologist at Nuffield Orthopaedic Centre, Oxford. Professor Wordsworth qualified in medicine from Westminster Hospital, University of Lon...

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Format:HardcoverDimensions:496 pagesPublished:April 19, 2016Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199607990

ISBN - 13:9780199607990

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Table of Contents

1. Introduction to clinical and biochemical disorders of the skeleton2. The physiology and pathology of bone3. Diagnosis and investigation4. Osteoporosis5. Osteomalacia and rickets6. Parathyroids and the skeleton7. Paget disease8. Neoplastic disease and other non-parathyroid causes of hypercalcaemia9. Osteogenesis imperfecta and other disorders of low bone density10. Skeletal dysplasias and related conditions11. Osteopetrosis and osteosclerosis12. Marfan syndrome and related disorders13. Ehlers-Danlos syndrome and related disorders14. Enzyme defects and the skeleton15. Fibrous dysplasia16. Fibrogenesis imperfecta ossium and other disorders of mineralization17. Ectopic mineralization18. Recent advances

Editorial Reviews

"In this excellent book, the authors have succeeded in clarifying the complex and potentially bewildering field of the molecular biology of the skeleton... The authors are to be congratulated on this magisterial book. The extent of their knowledge is prodigious, and with their clarity ofpresentation they have produced a masterpiece." --The Journal of Bone and joint Surgery, Vol 87, No 1