Paediatric Nephrology

Paperback | July 5, 2012

byLesley Rees, Paul A. Brogan, Detlef Bockenhauer

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Paediatric Nephrology is designed to help the reader understand and manage any condition affecting the kidney in childhood. It is pocket-sized to give easy reference in the clinical setting and highlights the important issues for quick use. From history taking and urinalysis, to acute renalfailure, transplantation and actute kidney injury, all aspects are covered in this concise yet comprehensive guide to this specialist area. It is an invaluable reference to the general paediatrician.The appendix provides useful additional information and protocols. This new edition is up-to-date and evidence-based, and tables and equations direct readers to correct drug dosages and use of relevant medication.

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Paediatric Nephrology is designed to help the reader understand and manage any condition affecting the kidney in childhood. It is pocket-sized to give easy reference in the clinical setting and highlights the important issues for quick use. From history taking and urinalysis, to acute renalfailure, transplantation and actute kidney inj...

Lesley Rees is Consultant Paediatric Nephrologist and Reader at University College London, and Great Ormond Street Hospital for Children NHS Trust, London, UK. Paul A. Brogan is Senior Lecturer and Honorary Consultant Paediatric Rheumatologist at University College London Institute of Child Health, and Great Ormond Street Hospital for ...
Format:PaperbackDimensions:624 pages, 7.09 × 3.94 × 0.01 inPublished:July 5, 2012Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199601372

ISBN - 13:9780199601370

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Table of Contents

Patient assessmentHistory and examinationAbnormalities of the urine and urinalysisThe approach to the child with haematuriaThe approach to the child with proteinuriaRadiological investigationsRecommendations for ultrasound screening for renal abnormalitiesFluid and electrolyte abnormalitiesPercutaneous renal biopsyGenetic testing and antenatal diagnosisThe neonateThe foetus and birthPerinatal 'bright' kidneysNeonatal disorders of fluid balanceNeonatal renal venous thrombosisCongenital abnormalitiesAntenatal diagnosis of structural renal abnormalitiesRenal agenesisHorseshoe kidney, renal ectopia and duplex kidneysThe multicystic dysplastic kidney (MCDK)Pelvi-ureteric junction (PUJ) abnormalitiesMegaureterPosterior urethral valvesUrogenital sinus and cloacal abnormalitiesAbsent abdominal musculature syndromeUrinary tract infectionBackground and clinical featuresCollection of urine samples and diagnosisBacterial and host factors that predispose to infectionManagementInvestigationsThe penis and foreskinVulvovaginitisEnuresisNocturnal enuresisPrimary diurnal and secondary enuresisBladder pathologyHomeostasisDisorders of sodium and water: Basic principlesDisorders of sodium and water: HypernatraemiaDisorders of sodium and water: HyponatraemiaDisorders of potassium: Basic principlesDisorders of potassium: HyperkalaemiaDisorders of potassium: HypokalaemiaDisorders of calcium: Basic principlesDisorders of calcium: HypercalcaemiaDisorders of calcium: HypocalcaemiaDisorders of magnesium: Basic principlesDisorders of magnesium:HypermagnesaemiaDisorders of magnesium: HypomagnesaemiaDisorders of phosphate: Basic principlesDisorders of phosphate: HyperphosphataemiaDisorders of phosphate: HypophosphataemiaDisorders of acid-base balance: Basic principlesDisorders of acid-base balance: AcidosisDisorders of acid-base balance: AlkalosisTubular diseaseDisorders of renal salt handling: Basic principlesDisorders of renal salt handling: Proximal tubuleDisorders of renal salt handling: Thick ascending limbDisorders of renal salt handling: Distal convoluted tubuleDisorders of renal salt handling: Collecting ductDisorders of renal water handlingDisorders of renal magnesium handlingRicketsTubulointerstitial nephritis (TIN)Renal calculi and nephrocalcinosisRenal calculiSpecific causes of calculi, their investigation and managementNephrocalcinosisGlomerular diseaseOverview of inherited glomerular diseasesAlport syndrome and thin basement membrane nephropathyAcute nephritisIgA Nephropathy (IgAN)Nephrotic syndromes: DefinitionsCongenital and Infantile Nephrotic SyndromeSteroid sensitive nephrotic syndrome: Presenting episodeSteroid sensitive nephrotic syndrome: Relapsing diseaseSteroid resistant nephrotic syndrome (SRNS)Systemic disease affecting the kidneySystemic lupus erythematosus: Background, clinical evaluation and investigationSystemic lupus erythematosus: Treatment of non-renal SLESystemic lupus erythematosus: Classification and treatment of lupus nephritisSystemic lupus erythematosus: B cell-targeted therapiesDiabetes and metabolic syndromeSickle cell diseaseRenal involvement in cystic fibrosisSarcoidosisMitochondrial cytopathiesFabry diseaseAmyloidosisThe emergency renal management of inborn errors of metabolism (IEMs)CystinosisVasculitisThe classification of paediatric vasculitisInvestigation of primary systemic vasculitisThe standard treatment of childhood vasculitisHenoch Schonlein purpuraKawasaki diseasePolyarteritis nodosa (PAN)The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitidesTakayasu arteritisInfections and the kidneyInfections and the kidneyRenal cystic diseases and ciliopathiesRenal cystic diseases: Basic principlesAutosomal Dominant Polycystic Kidney Disease (ADPKD)Renal structural abnormalities in Tuberous sclerosisAutosomal Recessive Polycystic Kidney Disease (ARPKD)Nephronophthisis (NPHP)Renal cysts and diabetes syndromeRenal dysplasiaSyndromes associated with renal diseasesOverviews of genetrics and renal abnormalities in inherited syndromesDown syndromeWilliams syndromeBranchio-oto-renal syndromeRenal tumoursWilms' tumourOther renal tumoursHypertensionBasic concepts of blood pressure, and defining hypertension in childrenMeasurement of blood pressure in infants and childrenThe investigation of hypertension in the youngRenovascular hypertensionTreatmentAmbulatory blood pressure measurement in childrenAcute kidney injuryBackground, pathophysiology and causesAssessment and investigationsManagementHypertensionNutrition in AKIDrug therapyDialysisFollow up of AKIHaemolytic uraemic syndrome (HUS): DefinitionsTypical (D+) HUS: Epidemiology and notesHUS: AtypicalRhabdomyolysisTumour lysis syndromeChronic kidney diseaseBackground and epidemiologyAssessment of renal functionInvestigation of the cause of CKDManagement: Overall aimsManagement: Fluid and electrolytesManagement: GrowthManagement: NutritionManagement: Use of recombinant human growth hormone (rhGH)Management: Enteral feedingManagement: Mineral and Bone Disorder (CKD-MBD)Management: AnaemiaManagement: Immunisation schedule for infants and childrenPreparation for renal replacement therapyChronic peritoneal dialysisPrinciples of peritoneal dialysisPeritoneal dialysis solutionsPeritoneal equilibrium test (PET)Peritonitis in patients on chronic peritoneal dialysisSclerosing peritonitisExtracorporeal treatmentsHaemodialysis: Principles of haemodialysisHaemodialysis: The machine, dialysate and waterHaemodialysis: Factors affecting the prescriptionHaemodialysis: ComplicationsHaemodialysis: AdequacyHaemodialysis: Vascular accessHaemodialysis: Blood-borne virusesContinuous renal replacement therapy (CRRT)Plasmapheresis and immunoadsorptionTransplantationRenal transplantation immunologyVaccination after transplantationKidney transplantation-the surgeryImmunosuppressive therapy in renal transplant patientsDiagnosis and treatment of transplant rejectionRecurrent and de novo renal disease following renal transplantationUrinary tract infection post transplantationNew onset diabetes after transplantationInfection post transplantMalignancy following renal transplantationGraft survival in transplant recipientsDrug prescribingBasic principlesSpecific drug issues of importanceIntraperitoneal drug dosesPsychosocial issuesEthical issuesNon-adherence in paediatric renal diseaseLong-term growthLong term survival of children on renal replacement therapyPalliative careAppendixAssessment of glomerular filtration rate (GFR)Furosemide test of urinary acidificationDDAVP testDisodium pamidronate infusionIntravenous cyclophosphamideGuidelines for the use of Basiliximab (Simulect)Protocol for administration of blood to patients with or approaching CKD 5Protocol for percutaneous transluminal angioplastyTravel information - Guidance for renal patientsGuidelines for the treatment of swine flu (H1N1) infection in children with renal diseaseMiscellaneous