Pathogenesis and Treatment of Diabetes Mellitus by J.K. Radder

Pathogenesis and Treatment of Diabetes Mellitus

byJ.K. Radder, H.H.P.J. Lemkes, H.M.J. Krans

Kobo ebook | December 6, 2012

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In this book on diabetes mellitus both the pathogenesis and treat­ ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol­ ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre­ disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto­ immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out­ break of the disease, the destructive process has already been active for years.

Title:Pathogenesis and Treatment of Diabetes MellitusFormat:Kobo ebookPublished:December 6, 2012Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9400943016

ISBN - 13:9789400943018

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