Peptide Receptors, Part II

Other | December 1, 2002

byBjorklund, A., A. Bjorklund

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Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complement
with chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry.


Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.




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From the Publisher

Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complementwith chapters covering six additional ...

Format:OtherDimensions:440 pages, 1 × 1 × 1 inPublished:December 1, 2002Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080538576

ISBN - 13:9780080538570

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Table of Contents

Preface. Subject Index. Opioid Receptors (C. Abbadie, G.W. Pasternak). The Melanin-Concentrating Hormone (H. Guillaumeet al.). Neuroanatomical Studies of the Opioid Receptor-like-1 Receptor and its Endogenous Neuropeptide Orphanin FQ (Nociceptin) (C.R. Neal Jr., H. Akil, S.J. Watson). Localisation of Galanin Receptor Subtypes in the Rat CNS (D. O'Donnellet al.). Orexin Receptors (T. Sakuraiet al.). Neurotensin receptors in the central nervous system (P. Sarret, A. Beaudet).