Pharmacology of 5-HT6 receptors, Part I

Other | December 1, 2010

byBorsini, Franco, Franco Borsini

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The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.



  • Written by expert researchers
  • Covers all published literature to date in the field of 5-HT6 receptors

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From the Publisher

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evalua...

Franco Borsini, Head, Central & Peripheral Nervous System and General Pharmacology Area - R&D Department, sigma-tau SpA, Pomezia (Rome), Italy

other books by Borsini, Franco

Pharmacology of 5-HT6 receptors, Part I
Pharmacology of 5-HT6 receptors, Part I

Hardcover|Nov 29 2010

$304.78 online$349.31list price(save 12%)
Format:OtherDimensions:224 pages, 1 × 1 × 1 inPublished:December 1, 2010Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123849772

ISBN - 13:9780123849779

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Table of Contents

  1. 5-HT6Medicinal Chemistry
  2. Kevin G. Liu and Albert J. Robichaud

  3. Patents
  4. Nicolas Vincent Ruiz and Gloria Oranias

  5. 5-HT6Receptor Charactertization
  6. Teresa Riccioni

  7. 5-HT6receptor signal transduction. Second Messenger Systems
  8. Xavier Codony, Javier Burgueño, Maria Javier Ramírez, José Miguel Vela

  9. Electrophysiology of 5-HT6Receptors
  10. Annalisa Tassone, Graziella Madeo, Giuseppe Sciamanna, Antonio Pisani, and Paola Bonsi

  11. Genetic Variations and Association
  12. Massimo Gennarelli and Annamaria Cattaneo

  13. Pharmacokinetics of 5-HT6Receptors Ligands

Angelo Mancinelli