Pharmacology of Neurotransmitter Release by Thomas C. SüdhofPharmacology of Neurotransmitter Release by Thomas C. Südhof

Pharmacology of Neurotransmitter Release

EditorThomas C. Südhof, Klaus Starke

Hardcover | December 18, 2007

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It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.
Title:Pharmacology of Neurotransmitter ReleaseFormat:HardcoverDimensions:596 pages, 9.25 × 6.1 × 0.98 inPublished:December 18, 2007Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540748040

ISBN - 13:9783540748045

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Table of Contents

Overview. Pharmacology of Neurotransmitter Release: Measuring Exocytosis. Preysnaptic Calcium Channels: Structure, Regulators, and Blockers. Pharmacology of Neurotansmitter Transport into Secretory Vesicles. Core Proteins of the Secretory Machinery. Presynaptic Neurotoxins with Enzymatic Activities. a-Latrotoxin and Its Receptors. Presynaptic signaling by heterotrimeric G-proteins. Presynaptic Receptors for Acetylcholine, and Adrenaline/Noradrenaline. Presynaptic receptors for dopamine, histamine and serotonin. Presynaptic Adenosine and P2Y Receptors. Presynaptic Metabotropic Glutamate and GABAB Receptors. Presynaptic Neuropeptide Receptors. Presynaptic Modulation by Endocannabinoids. Presynaptic Ionotropic Receptors. NO/cGMP-Dependent Modulation of Synaptic Transmission. Therapeutic Use of Release-Modifying Drugs.