Pharmacology Of Purine And Pyrimidine Receptors

Hardcover | June 1, 2011

byJoel LindenEditorKenneth A Jacobson

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This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development

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This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development

Format:HardcoverDimensions:558 pages, 9 × 6 × 0.98 inPublished:June 1, 2011Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123855268

ISBN - 13:9780123855268

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Table of Contents

  1. The structure of the adenosine receptors: implications for drug discovery
  2. J. Robert Lane, Veli-Pekka Jaakola, Adriaan P. IJzerman

  3. Adenosine Receptors in Health and Disease
  4. Stefania Gessi, Stefania Merighi, Katia Varani, and Pier Andrea Borea

  5. Adenosine and the Regulation of Metabolism and Body Temperature
  6. Bertil Fredholm, Stina M. Johansson and Ying-Qing Wang

  7. Regulation of Leukocyte Function by Adenosine Receptors
  8. Joel Linden

  9. Role of Adenosine A2B Receptors in Inflammation
  10. Igor Feoktistov and Italo Biaggioni

  11. Interplay of Hypoxia and A2B Adenosine Receptors in Tissue Protection
  12. Michael Koeppen, Tobias Eckle, and Holger Eltzschig

  13. Allosteric Modulation of Purine and Pyrimidine Receptors
  14. Kenneth Jacobson, Zhan-Guo Gao, Aniko Göblyös, and Adriaan IJzerman

  15. Molecular Mechanisms of Purine and Pyrimidine Nucleotide Release
  16. Eduardo R. Lazarowski, Juliana I. Sesma, Lucia Seminario-Vidal, and Silvia M. Kreda

  17. Impact of Ectoenzymes on Purinergic Signalling
  18. Filip Kukulski, Sébastien A. Lévesque, and Jean Sévigny

  19. Ectonucleotidases as Regulators of Purinergic Signaling in Inflammation and Thrombosis
  20. Simon C. Robson and Silvia Deaglio

  21. P2X Receptors in Health and Disease
  22. Geoffrey Burnstock and Charles Kennedy

  23. Molecular Pharmacology, Physiology, and Structure of the P2Y Receptors
  24. Ivar von Kügelgen and T. Kendall Harden2

  25. P2Y Receptors in Health and Disease
  26. David Erlinge

  27. P2 Receptor Signaling in Neurons and Glia of the Central Nervous System
  28. Laszlo Köles Anna Leichsenring, Patrizia Rubini and Peter Illes

  29. Role of Purinergic Receptors in Neuroprotection

Tozaki-Saitoh Hidetoshi, Makoto Tsuda, and Kazuhide Inoue