Physiologically Based Pharmacokinetic Modeling: Science and Applications

June 23, 2005|
Physiologically Based Pharmacokinetic Modeling: Science and Applications by Micaela Reddy
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A definitive, single source of information on PBPK modeling
Physiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling purposes so users can quickly access information, this is the first comprehensive reference of its kind.
This book presents an overview of the underlying principles of PBPK model development. Then it provides a compendium of PBPK modeling information, including historical development, specific modeling challenges, and current practices for:
* Halogenated Alkanes
* Halogenated Alkenes
* Alkene and Aromatic Compounds
* Reactive Vapors in the Nasal Cavity
* Alkanes, Oxyhydrocarbons, and Related Compounds
* Pesticides and Persistent Organic Pollutants
* Dioxin and Related Compounds
* Metals and Inorganic Compounds
* Drugs
* Antineoplastic Agents
* Perinatal Transfer
* Mixtures
* Dermal Exposure Models
In addition to pinpointing specific information, readers can explore diverse modeling techniques and applications. An authoritative reference for toxicologists, ecotoxicologists, risk assessors, regulators, pharmacologists, pharmacists, and graduate students in pharmacokinetics and toxicology, Physiologically-Based Pharmacokinetic Modeling compiles information from leaders in the field and discusses future directions for PBPK modeling.
The EDITORS have worked together on PBPK research and in teaching PBPK modeling workshops and courses through the Quantitative and Computation Toxicology research group at the Center for Environ-mental Toxicology and Technology (CETT) in the Department of Environmental and Radiological Health Sciences at Colorado State University (CSU)...
Title:Physiologically Based Pharmacokinetic Modeling: Science and ApplicationsFormat:HardcoverProduct dimensions:420 pages, 9.43 X 6.48 X 0.96 inShipping dimensions:420 pages, 9.43 X 6.48 X 0.96 inPublished:June 23, 2005Publisher:WileyLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0471478148

ISBN - 13:9780471478140

Appropriate for ages: All ages

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