Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy by Stephen B. HowellPlatinum and Other Metal Coordination Compounds in Cancer Chemotherapy by Stephen B. Howell

Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

byStephen B. HowellEditorStephen B. Howell

Hardcover | February 29, 1992

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Title:Platinum and Other Metal Coordination Compounds in Cancer ChemotherapyFormat:HardcoverDimensions:558 pages, 9.21 × 6.14 × 0 inPublished:February 29, 1992Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:030644027X

ISBN - 13:9780306440274

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Table of Contents

Synthetic Chemistry and Biochemistry: Platinum DNA Chemistry; S. Lippard. New Insights about the Interaction of Cisplatinum with Intracellular Components; J. Reedijk. Modelling Platinum-DNA Interactions; B. Lippert. From the Modelization of DNA Platination to the Conception of New Drugs; J.C. Chottard. Biochemical and Molecular Pharmacology: Role of Membrane Ion Transport in Cisplatin Accumulation; P.A. Andrews. Enhancement of the Antiproliferative Effect of Cisdiamminedichloroplatinum (II) and Other Antitumor Agents by Inhibitors of Enzymes Involved in Growth Factor SignalTransduction; H.H. Grunicke. Signal Transduction Pathway Regulation of DDP Sensitivity; S.B. Howell. The Role of Platinum-DNA Lesions in the Inhibition of DNA Replication; N.P. Johnson. Toxicology and Clinical Pharmacology of New Drugs: Pharmacokietics of Carboplatin in Children and the Development of a Pediatric Dose Equation; H. Calvert. Clinical Studies with Cisplatin Analogues, 254S, DWA2114R and NK121; H. Majima. Clinical Trials: Dose Intensity Analysis May Help Resolve Issues in Chemotherapy with Platinum Compounds; W. Hryniuk. Cisplatin DoseIntensity in Testicular Cancer Treatment: Analysis of a Randomized Clinical Trial; C.R. Nichols, et al. 39 additional articles. Index.