Polycystic Kidney Disease by Michael L. WatsonPolycystic Kidney Disease by Michael L. Watson

Polycystic Kidney Disease

EditorMichael L. Watson, Vicente E. Torres

Hardcover | October 1, 1982

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Many inherited diseases and non-hereditary disorders have in common the development of renal cystic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation. Since the publication six years ago of the last book on polycystic kidney disease, a number of genes causing the disease have been identified, mapped, or sequenced; new experimental models and the application of molecular biology techniques have provided new insights into the pathogenesis Rpolycystic kidney disease; novel clinical studies have provided valuable information for the prevention, evaluation, and treatment of the complications of this disease. This book provides an updated, state-of-the-art review of the genetics, pathophysiology, evaluation, and management of thesediseases and will be of interest to both basic researchers and clinicians in nephrology.
Michael L. Watson is at University of Edinburgh. Vicente E. Torres is at The Mayo Clinic, Minnesota.
Title:Polycystic Kidney DiseaseFormat:HardcoverDimensions:606 pages, 9.45 × 6.61 × 1.5 inPublished:October 1, 1982Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0192625780

ISBN - 13:9780192625786


Table of Contents

Part I: Cystic renal disease: experimental models and pathology1. Principles of molecular biology as applied to the study of disease2. In vitro models in the study of renal cystogenesis3. Mouse models of polycystic kidney disease4. In vivo models in non-murine species5. Pathogenesis of polycystic kidney disease: basement membrane and extracellular matric6. Pathogenesis of polycystic kidney disease: altered cellular functionPart II: Cystic renal disease: clinical spectrum7. Classification of cystic kidneys8. Diagnostic imaging of renal cystic diseases9. Autosomal recessive polycystic kidney disease: clinical and genetic profiles10. Acquired renal cystic disease11. Tuberous sclerosiscomplex12. Von Hippel-Lindau DiseasePart III: Adult polycystic kidney disease: natural history and genetics13. Definition and natural history of autosomal dominant polycystic kidney disease14. Cloning strategies and genetics of type 1 autosomal dominant polycystic kidney diseasePart IV: Adult polycystic kidney disease: clinical features16. Hypertension in polycystic kidney disease17. Progression to renal insufficiency18. Management of end-stage renal failure and problems of transplantation in autosomal dominant polycystic kidney disease19. Chronic pain and its medical and surgical management in renal cystic diseasePart V: Adult polycystic kidney disease: complications20. Miscellaneous renal and systemic complications of autosomal dominant polycystic kidney disease including infection21. Polycystic liver disease22. Intracranial aneurysms in autosomal dominant polycystic kidney disease23. Particular problems in childhood and adolescents in autosomal dominant polycystic kidney disease24. Counselling and ethical considerations in autosomal polycystic kidney disease

Editorial Reviews

`This is a further addition to the 'Oxford Clinical Nephrology' Series and provides an extensive review of our current knowledge on polycystic kidney disease...Overall this is an excellent book and provides much useful information for both the diagnosis and management of renal cystic diseases.It can be highly recommended, not just for the outstanding way the subject has been approached, but because the book also contains useful background information which greatly enhances the overall value.'Nephrol Dial Transplant, 1998, 13: 1904-1908