Post-genome Informatics

Paperback | January 20, 2000

byMinoru Kanehisa

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The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional dataabout genes such as gene expression profiles at a rapid rate. There is therefore a large and ever increasing amount of data about genes and molecules. However there is still a huge gap between information at the molecular level and information at the level of integrated biological systems. It isthis gap that is addressed in Post-genome Informatics. Post-genome informatics is the analysis of biological functions in terms of the network of interacting molecules and genes with the aim of understanding how a biological system is organized from its individual building blocks. As well ascontaining a comprehensive survey of the database and computational technologies relevant to molecular sequence analysis, Post-genome Informatics will provide the reader with a conceptual framework and practical methods for the representation and computation of molecular networks.

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From the Publisher

The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional dataabout genes such as gene expression profiles at...

Professor Kanehisa is a Principal Investigator in the Genome Informatics Project in Japan. He speaks widely on the subject and is on the editorial board of the journal Bioinformatics.
Format:PaperbackPublished:January 20, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198503261

ISBN - 13:9780198503262

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Table of Contents

PrefaceBlueprint of lifeMolecular biology databases - Historical background, Informatics technologies, New generation of molecular biology databasesSequence analysis of nucleic acids and proteins - Similarity search, Prediction of structures and functionsNetwork analysis of molecular interactions - Network representation and computation, Principles of biochemical networksReferences and further reading

Editorial Reviews

"As a whole the first three chapters would make a valuable basis for tutorial discussions for a final-year graduate students in Bioinformatics." Journal of Cell Science