Post-genome Informatics by Minoru Kanehisa

Post-genome Informatics

byMinoru Kanehisa

Paperback | January 20, 2000

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The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional dataabout genes such as gene expression profiles at a rapid rate. There is therefore a large and ever increasing amount of data about genes and molecules. However there is still a huge gap between information at the molecular level and information at the level of integrated biological systems. It isthis gap that is addressed in Post-genome Informatics. Post-genome informatics is the analysis of biological functions in terms of the network of interacting molecules and genes with the aim of understanding how a biological system is organized from its individual building blocks. As well ascontaining a comprehensive survey of the database and computational technologies relevant to molecular sequence analysis, Post-genome Informatics will provide the reader with a conceptual framework and practical methods for the representation and computation of molecular networks.

About The Author

Professor Kanehisa is a Principal Investigator in the Genome Informatics Project in Japan. He speaks widely on the subject and is on the editorial board of the journal Bioinformatics.

Details & Specs

Title:Post-genome InformaticsFormat:PaperbackPublished:January 20, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198503261

ISBN - 13:9780198503262

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Table of Contents

PrefaceBlueprint of lifeMolecular biology databases - Historical background, Informatics technologies, New generation of molecular biology databasesSequence analysis of nucleic acids and proteins - Similarity search, Prediction of structures and functionsNetwork analysis of molecular interactions - Network representation and computation, Principles of biochemical networksReferences and further reading

Editorial Reviews

"As a whole the first three chapters would make a valuable basis for tutorial discussions for a final-year graduate students in Bioinformatics." Journal of Cell Science