Potential Neuromodulatory Profile of Phytocompounds in Brain Disorders

Potential Neuromodulatory Profile of Phytocompounds in Brain Disorders

Paperback | February 13, 2017

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Natural and chemical compounds, often used as both dietary supplements and alternative medicines, are characterized by specific chemical properties, allowing their passage across the blood brain barrier with consequent specific effects on neurotransmission. In particular, several natural compounds have shown beneficial properties in the treatment of neuropsychiatric disorders, especially cognitive impairment and mood disorders, contributing to the maintenance of the physiological brain functioning by interacting with different receptors, transcription factors and signal transduction pathways. Neuroinflammation and oxidative stress have also been proposed as crucial contributors to brain dysfunction development, thus recent investigations have focused on novel therapeutic approaches based on the use of phytoderivates with neuroprotective properties. Thus, this Special Issue includes a collection of 11 papers, describing key findings for the identification of molecular mechanisms required for the development of potential and promising natural therapeutics for the treatment of psychiatric and neurodegenerative disorders.

Title:Potential Neuromodulatory Profile of Phytocompounds in Brain DisordersFormat:PaperbackProduct dimensions:220 pages, 9.61 X 6.69 X 0.6 inShipping dimensions:220 pages, 9.61 X 6.69 X 0.6 inPublished:February 13, 2017Publisher:MDPI AGLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3038423165

ISBN - 13:9783038423164

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Table of Contents

1) Editorial: Special Issue “Potential Neuromodulatory Profile of Phytocompounds in Brain
Disorders”
2) Antidepressant Potential of Chlorogenic Acid-Enriched Extract from Eucommia ulmoides
Oliver Bark with Neuron Protection and Promotion of Serotonin Release through Enhancing
Synapsin I Expression
3) Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
4) 3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced
Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus
5) Protective Effects of Costunolide against Hydrogen Peroxide-Induced Injury in PC12 Cells
6) Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known
Alzheimer’s Disease Target
7) Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the
Clinical Evidence?
8) Therapeutic Effects of Phytochemicals and Medicinal Herbs on Chemotherapy-Induced
Peripheral Neuropathy
9) The Suppressive Effects of Cinnamomi Cortex and Its Phytocompound Coumarin on Oxaliplatin-
Induced Neuropathic Cold Allodynia in Rats
10) The Anticonvulsant Activity of a Flavonoid-Rich Extract from Orange Juice Involves both NMDA
and GABA-Benzodiazepine Receptor Complexes
11) Chlorella sorokiniana Extract Improves Short-Term Memory in Rats
12) Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?