Principles Of Translational Science In Medicine: From Bench To Bedside

Hardcover | April 7, 2015

byMartin WehlingEditorMartin Wehling

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Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities NCEs or NBEs as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population the elderly , case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

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From the Publisher

Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional an...

Format:HardcoverDimensions:364 pages, 9.41 × 7.24 × 0.98 inPublished:April 7, 2015Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128006870

ISBN - 13:9780128006870

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Table of Contents

1. Introduction and Definitions 2. What Is Translational Medicine? 3. Tools 4. Biomarkers 5. Early Clinical Trial Design 6. Pharmaceutical Toxicology 7. Translational Science Biostatistics 8. Intellectual Property Rights in Translation 9. Translational research in the Elderly 10.The View of Big Pharma 11. Translational Science in Medicine: Putting the Pieces Together 12. Biomarkers, Early Human Trials, Networking, Translatability Assessment 13. Learning by Experience: Examples of Translational Processes in the Cardiovascular Field