Programmed Cell Death in Cancer Progression and Therapy by Roya Khosravi-farProgrammed Cell Death in Cancer Progression and Therapy by Roya Khosravi-far

Programmed Cell Death in Cancer Progression and Therapy

EditorRoya Khosravi-far, Eileen White

Hardcover | January 7, 2008

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Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.
Title:Programmed Cell Death in Cancer Progression and TherapyFormat:HardcoverDimensions:370 pagesPublished:January 7, 2008Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1402065531

ISBN - 13:9781402065538

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Table of Contents

IntroductionChapter 1: Cell Death: History and Future by Zahra Zakeri and Richard A. LockshinChapter 2: Caspase Mechanisms by Guy S. Salvesen and Stefan J. RiedlChapter 3: The Mitochondrial Death Pathway by Anas Chalah and Roya Khosravi-FarChapter 4: Apoptotic Pathways in Tumor Progression and Therapy by Armelle Melet, Keli Song, Octavian Bucur , Zainab Jagani, Alexandra R. Grassian and Roya Khosravi-FarChapter 5: Therapeutic Targeting of Death Pathways in Cancer - Mechanisms for activating cell death in cancer cells by Ting-Ting Tan and Eileen WhiteChapter 6: Overcoming Resistance to Apoptosis in Cancer Therapy by Peter Hersey, X.D. Zhang, N. MhaidatChapter 7: TRAIL Receptors: Targets for Cancer Therapy by Robin C. Humphreys and Wendy HalpernChapter 8: Rational Design of Therapeutics Targeting the Bcl-2 Family - Are some cancer cells primed for death but waiting for a final push? by Victoria Del Gaizo Moore and Anthony LetaiChapter 9: Autophagy and Tumor Suppression - Recent advances in understanding the  link between autophagic cell death pathways and tumor development by Shani Bialik and Adi KimchiChapter 10: Regulation of Programmed Cell Death by the p53 Pathway by Kageaki Kuribayashi and Wafik S. El-DeiryChapter 11: Regulation Of Programmed Cell Death by Nf-k B and its Role in Tumorigenesis and Therapy by Yongjun Fan, Jui Dutta, Nupur Gupta, Gaofeng Fan and Céline GélinasChapter 12: Targeting Proteasomes as Therapy in Multiple Myeloma by Dharminder Chauhan, Teru Hideshima and Kenneth C. AndersonChapter 13: Histone Deacetylase Inhibitors: Mechanisms and Clinical Significance in Cancer - HDAC inhibitor-induced apoptosis by Sharmila Shankar and Rakesh K. SrivastavaChapter 14: RNA Interference and Cancer: Endogenous Pathways and Therapeutic Approaches by Derek M. Dykxhoorn, Dipanjan Chowdhury, Judy LiebermanChapter 15: Cancer Stem Cells and Impaired Apoptosis by Zainab Jagani and Roya Khosravi-Far

Editorial Reviews

From the reviews:"Programmed cell death (PCD) is an intriguing term that was introduced by Richard Lockshin nearly 45 years ago. . this book is about PCD with intense focus on apoptosis and the exploitation of PCD for treating cancer. . All chapters are well edited and thoroughly referenced. The nicety of the book is the use of numerous color figures. In my opinion, both scientists and clinicians, experienced or beginning, will profit from a thoughtful reading of Programmed Cell Death in Cancer Progression and Therapy." (A. A. Philchenkov, Biochemistry (Moscow), Vol. 74 (4), 2009)