Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology and Therapeutics by J. CheronisProteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology and Therapeutics by J. Cheronis

Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology…

byJ. Cheronis, Repine

Paperback | April 19, 2012

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Title:Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology…Format:PaperbackDimensions:248 pages, 24.4 × 17 × 0.02 inPublished:April 19, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3034873999

ISBN - 13:9783034873994

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Table of Contents

Overview.- Proteases - Structures, Mechanisms and Inhibitors.- Biochemical Mechanisms for Disrupting the Proteinase-Proteinase Inhibitor Balance in Tissues.- Oxidants, Metalloproteases and Serine Proteases in Inflammation.- Elastase and Oxygen Radicals: Synergistic Interactions.- Neutrophil Elastase Inhibitors: Clinical Potential.- Proteolysis-Induced Pathomechanisms in Acute Inflammation and Related Therapeutic Approaches.- Synthesis and Characterization of Human Neutrophil Elastase Inhibitors Derived from Aromatic Esters of Phenylalkanoic Acids.- In Vivo Evaluation of MDL 201,404YA, A Novel Inhibitor of Human Neutrophil Elastase.- Alpha1-Antitrypsin Augmentation Therapy.- Secretory Leukocyte Protease Inhibitor in Cystic Fibrosis.- Oxidation Resistant Muteins of Antileukoproteinase as Potential Therapeutic Agents.- Proteases and Protease-Derived Peptides in Inflammation.- Factor XII Activation and Inhibition in Inflammation.- The Kinin System in Inflammation.- Role of Bradykinin in Microbial Infection: Enhancement of Septicemia by Microbial Proteases and Kinin.- Kinin Antagonists as Human Therapeutics.- Proteases in Immunoregulation and Cellular Differentiation.- Cytokine Regulation of Endothelial Cell Extracellular Proteolysis.- Different Functional Share of Individual Lysosomal Cathepsins in Normal and Pathological Conditions.- Neuropeptide Processing in Pathophysiology.- Resolution of limp-Free and Timp-Complexed 70kDa Progelatinase from Culture Medium of Rous Sarcoma Virus-Transformed Chicken.- Endotoxin and Eicosanoids.