Protein Aggregation And Fibrillogenesis In Cerebral And Systemic Amyloid Disease by J. Robin HarrisProtein Aggregation And Fibrillogenesis In Cerebral And Systemic Amyloid Disease by J. Robin Harris

Protein Aggregation And Fibrillogenesis In Cerebral And Systemic Amyloid Disease

byJ. Robin Harris

Paperback | January 29, 2015

Pricing and Purchase Info


Earn 1,725 plum® points

Prices and offers may vary in store


In stock online

Ships free on orders over $25

Not available in stores


This volume of the Subcellular Biochemistry series is the result of the long-standing research interest of the editor in the molecular mechanism underlying Alzheimer's disease and other amyloid diseases, indicated also by the earlier book in the series (Volume 38), devoted to Alzheimer's disease. The broad coverage within the present amyloidogenesis book represents an attempt to collate current knowledge relating to the proteins and peptides involved in most of the known amyloid diseases, together with some amyloid/fibril-forming proteins and peptides that are not involved in diseases. Thus, the range of topics included is comprehensive and furthermore it was thought appropriate to include both basic science and clinical presentation of the subjects under discussion.
Title:Protein Aggregation And Fibrillogenesis In Cerebral And Systemic Amyloid DiseaseFormat:PaperbackDimensions:650 pages, 23.5 × 15.5 × 0.02 inPublished:January 29, 2015Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9400797362

ISBN - 13:9789400797369

Look for similar items by category:


Table of Contents

I. Introduction

1. Introduction and Technical Survey;J. Robin HarrisandNathaniel G. Milton

II. Basic Science

2. Fibril Formation by Short Synthetic Peptides;Andrew Smith

3. In vitroOligomerization and Fibrillogenesis of Amyloid-beta Peptides;NúriaBenseny-Cases, Oksana Klementieva and Josep Cladera

4. Tau Fibrillogenesis;Nitin Chaudhary and Ramakrishnan Nagaraj

5. Prion protein Aggregation and FibrillogenesisIn vitro;Jan Stöhr

6. α-Synuclein Aggregation and Modulating Factors;Katerina E. Paleologou and Omar M. A. El-Agnaf

7. Pathological Self-aggregation of β2-microglobulin: A Challenge for Protein Biophysics;Gennaro Esposito, Alessandra Corazza, and Vittorio Bellotti

8. Islet amyloid polypeptide - Aggregation and fibrillogenesisin vitroand its Inhibition;Janine Seeliger and Roland Winter

9. Mechanisms of Transthyretin Aggregation and Toxicity;Robert J. Gasperini, David W. Klaver, Xu Hou, Marie-Isabel Aguilar and David H. Small

10. Fibrillogenesis of Huntingtin and Other Glutamine Containing Proteins;Yuri L. Lyubchenko, Alexey V. Krasnoslobodtsev and Sorin Luca

11. Aggregation and Fibrillogenesis of Proteins not Associated with Disease - A few Case Studies;Moritz Lassé, Juliet A. GerrardandF. Grant Pearce

12. Experimental Inhibition of Peptide Fibrillogenesis by Synthetic Peptides, Carbohydrates and Drugs;Alagiri Srinivasan

13. Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (Aβ) and other disease-related peptides/proteins by plant extracts and herbal compounds;Suresh Kumar, Edward Okello and J. Robin Harris

III. Clinical Science: The Cerebral and Systemic Amyloid Diseases

Pathogenesis and therapeutic consideration of the major disorders

14. Alzheimer's Disease;Vanessa J. De-Paula, Marcia Radanovic, Breno S. Diniz, Orestes V. Forlenza

15. Modeling the Polyglutamine Aggregation Pathway in Huntington's Disease: from Basic Studies to Clinical Applications;
Keizo Sugaya

16. Parkinson's Disease;Timothy R. Mhyre, James T. Boyd, Robert W. Hamill, and Kathleen Maguire-Zeiss

17. Human Prion Diseases: From Kuru to Variant Creutzfeldt-Jakob Diseasae;Beata Sikorska and PaweÅ P. Liberski

18. Animal Prion Diseases;Otto Windl and Mike Dawson

19. β2-microglobulin Amyloidosis;Dorthe B. Corlin and Niels H.H. Heegaard

20. Systemic AA Amyloidosis;Jennifer H Pinney and Helen J Lachmann

21. Familial Amyloidotic Polyneuropathy and Transthyretin;Takamura Nagasaka22. The Challenge of Systemic Immunoglobulin Light-chain Amyloidosis (AL);Giovanni Palladini and Raymond L Comenzo