Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign by Jinbo XuProtein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign by Jinbo Xu

Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalign

byJinbo Xu, Sheng Wang, Jianzhu Ma

Paperback | March 3, 2015

Pricing and Purchase Info

$81.74

Earn 409 plum® points

Prices and offers may vary in store

Quantity:

In stock online

Ships free on orders over $25

Not available in stores

about

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.
Title:Protein Homology Detection Through Alignment of Markov Random Fields: Using MRFalignFormat:PaperbackPublished:March 3, 2015Publisher:Springer International PublishingLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:331914913X

ISBN - 13:9783319149134

Look for similar items by category:

Reviews

Table of Contents

Introduction

Method

Software

Experiments and Results

Conclusion