Protein Kinase Technologies by Hideyuki MukaiProtein Kinase Technologies by Hideyuki Mukai

Protein Kinase Technologies

byHideyuki Mukai

Hardcover | May 31, 2012

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Divided into two convenient sections,Protein Kinase Technologiescollects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience. These chapters will not only be practical instructions useful for readers' daily work in setting up and performing research but also thought-provoking and enjoyable reviews of recent advancements of individual protein kinases in neuroscience. Written for the highly successfulNeuromethodsseries, this work contains the kind of detailed description and implementation advice that is crucial for getting optimal results.

Authoritative and accessible,Protein Kinase Technologiesseeks to foster cross-talk among investigators who study different protein kinases, and will also be beneficial for the entry of new investigators into this pivotal field.

Title:Protein Kinase TechnologiesFormat:HardcoverDimensions:366 pagesPublished:May 31, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617798231

ISBN - 13:9781617798238

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Table of Contents

Part I: Recent General Methodologies

1. Visualization of Protein Kinase Activities in Living Cells

Kazuhiro Aoki, Naoki Komatsu, Akihiro Goto, and Michiyuki Matsuda

2. Phos-Tag Affinity Electrophoresis for Protein Kinase Profiling

Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike

3. Large-Scale Protein Phosphorylation Analysis by Mass Spectrometry-Based Phosphoproteomics

Wei-Chi Ku, Naoyuki Sugiyama, and Yasushi Ishihama

Part II: Individual Protein Kinases

4. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)

Steven J. Coultrap and K. Ulrich Bayer

5. CASK: A Specialized Neuronal Kinase

15. Diacylglycerol Kinase (DGK)

Konark Mukherjee

6. Cyclin-Dependent Kinase 5 (Cdk5): Preparation and Measurement of Kinase Activity

15. Diacylglycerol Kinase (DGK)

Seiji Minegishi and Shin-ichi Hisanaga

7. ErbB Membrane Tyrosine Kinase Receptors: Analyzing Migration in a Highly Complex Signaling System

15. Diacylglycerol Kinase (DGK)

Nicole M. Brossier, Stephanie J. Byer, Lafe T. Peavler, and Steven L. Carroll

8. The Extracellular-Signal Regulated Kinase (ERK) Cascade in Neuronal Cell Signaling

15. Diacylglycerol Kinase (DGK)

Daniel Orellana, Ilaria Morella, Marzia Indrigo, Alessandro Papale, and Riccardo Brambilla

9. Glycogen Synthase Kinase-3 in Neurological Diseases

15. Diacylglycerol Kinase (DGK)

Oksana Kaidanovich-Beilin and James Robert Woodgett

10. Cortical Neurons Culture to Study c-Jun N-Terminal Kinase Signaling Pathway

15. Diacylglycerol Kinase (DGK)

Alessandra Sclip, Xanthi Antoniou, and Tiziana Borsello

11. MuSK: A Kinase Critical for the Formation and Maintenance of the Neuromuscular Junction

15. Diacylglycerol Kinase (DGK)

Arnab Barik and Lin Mei

12. Assays for Pten-Induced Novel Kinase 1 (PINK1) and Leucine-Rich Repeat Kinase 2 (LRRK2), Kinases Associated with Parkinson's Disease

15. Diacylglycerol Kinase (DGK)

Alexandra Beilina and Mark R. Cookson

15. Diacylglycerol Kinase (DGK)

13. Imaging PKA Activation Inside Neurons in Brain Slice Preparations

15. Diacylglycerol Kinase (DGK)

Marina Brito, Elvire Guiot, and Pierre Vincent

14. Imaging Oscillations of Protein Kinase C Activity in Cells

15. Diacylglycerol Kinase (DGK)

Maya T. Kunkel and Alexandra C. Newton

Yasuhito Shirai and Naoaki Saito

16. Trafficking of Trk Receptors

Daniel Bodmer and Rejji Kuruvilla

17. Mammalian Target of Rapamycin

Lukasz Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, and Jacek Jaworski

18. Protein Kinase G (PKG): Involvement in Promoting Neural Cell Survival, Proliferation, Synaptogenesis, and Synaptic Plasticity and the Use of New Ultrasensitive Capillary-Electrophoresis-Based Methodologies for Measuring PKG Expression and Molecular Actions

Ronald R. Fiscus and Mary G. Johlfs

19. Electrophysiological Technique for Analysis of Synaptic Function of PKN1 in Hippocampus

Hiroki Yasuda and Hideyuki Mukai

15. Diacylglycerol Kinase (DGK)

Yasuhito Shirai and Naoaki Saito

16. Trafficking of Trk Receptors

Daniel Bodmer and Rejji Kuruvilla

17. Mammalian Target of Rapamycin

Lukasz Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, and Jacek Jaworski

18. Protein Kinase G (PKG): Involvement in Promoting Neural Cell Survival, Proliferation, Synaptogenesis, and Synaptic Plasticity and the Use of New Ultrasensitive Capillary-Electrophoresis-Based Methodologies for Measuring PKG Expression and Molecular Actions

Ronald R. Fiscus and Mary G. Johlfs

19. Electrophysiological Technique for Analysis of Synaptic Function of PKN1 in Hippocampus

Hiroki Yasuda and Hideyuki Mukai