Protein Modules and Protein-Protein Interactions

Other | November 1, 2002

byJanin, Joël|, Joël Janin

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Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.

Key Features
* Comprehensive overview of different facets of macromolecule interactions
* Computational and bioinformatics aspects of analyzing protein modules and their interactions
* Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes

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From the Publisher

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging fr...

Format:OtherDimensions:333 pages, 1 × 1 × 1 inPublished:November 1, 2002Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080493750

ISBN - 13:9780080493756

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Table of Contents

Protein Modules and Protein-Protein Interaction: Toward a Global View
Structural Basis for Affinity and Specificity in Macromolecular Recognition
Sequence Analysis of Multidomain Proteins: Past Perspectives and Future Directions
Identification of Transiently Interacting Proteins and of Stable Protein Complexes
Molecular Recognition in Antibody-Antigen Complexes
Molecular Recognition by SH2 Domains
How SH3 Domains Recognize Proline
Structural Biology of eIF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation