Protein Targeting: Protein Targeting

Paperback | April 30, 1999

EditorStella M. HurtleyAs told byHurtley

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Protein targeting is the study of how proteins suynthesized in one part of the cell reach their ultimate destination. A cell may have to guide a protein through several membranes into one of its organelles, or take up or secrete a protein through its cell wall. This book is a preview of thelatest research in this area, which has applications for understanding cancer, studying diseases that result from faulty targeting, and genetic manipulation of microorganisms to target useful proteins.

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Protein targeting is the study of how proteins suynthesized in one part of the cell reach their ultimate destination. A cell may have to guide a protein through several membranes into one of its organelles, or take up or secrete a protein through its cell wall. This book is a preview of thelatest research in this area, which has applic...

From the Jacket

This volume addresses one of the fundamental problems of cell biology, namely how proteins are sent to, and maintained at, their correct destinations. Individual chapters provide up-to-date information on protein targeting to different cell organelles; the nucleus, mitochondria, peroxisomes, endoplasmic reticulum, and the Golgi complex...

Stella M. Hurtley is associate editor, Science International, Cambridge

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Format:PaperbackDimensions:234 pages, 9.69 × 7.44 × 0.71 inPublished:April 30, 1999Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0199635617

ISBN - 13:9780199635610

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Table of Contents

1. Targeting precursor proteins to mitochondria2. Protein transport to the nucleus and its regulation3. Targeting and import of peroxisomal proteins4. Protein translocation into the endoplasmic reticulum5. ER-Golgi membrane traffic and protein targeting6. Biogenesis of constitutive secretory vesicles, secretory granules and synaptic vesicles - facts and concepts7. Protein sorting during endocytosis

Editorial Reviews

`'...is a very useful attempt to give an overview of the present state of knowledge and also to show where furhter progress is needed...This book should be read by anyone interested in the organisation and control of cell functions. The non specialist would find it an interesting book to scanthrough, while those with a more specialist interest would find it a useful addition to their shelves.''P.J.Davey, Br.J.Boimed Sci 1998; 55.