Psychiatric Genetics and Genomics

Paperback | October 21, 2005

EditorPeter McGuffin, Michael J Owen, Irving I Gottesman

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Revised for paperback edition, with new appendices Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may havepsychiatric presentations. The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes,amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.

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Revised for paperback edition, with new appendices Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may...

Peter McGuffin is at SGDP Centre, Institute of Psychiatry, Denmark Hill, London, UK. Michael J Owen is in the Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK. Irving Gottesman is at the University of Minnesota.

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Format:PaperbackDimensions:504 pages, 9.45 × 6.61 × 1.08 inPublished:October 21, 2005Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198564864

ISBN - 13:9780198564867

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Table of Contents

Part 1: Basic Principles1. Owen and O'Donovan: Basic molecular genetics2. McGuffin and Cardno: Quantitative genetics3. Sham and McGuffin: Linkage and associationPart 2: The Genetics of Normal and Abnormal Development4. Plomin, Happe and Caspi: Personality and cognitive abilities5. Thapar and Clayton-Smith: Genetics of mental retardation6. Williams: Reading and language disorders7. Thapar: Childhood disordersPart 3: The Genetics of Abnormal Behaviour in Adult Life8. McGuffin, Moffitt and Thapar: Personality disorders9. Jones, Kent and Craddock: Genetics of affective disorders10. Owen, O'Donovan and Gottesman: Schizophrenia11. Ball and Collier: Substance misuse12. Eley, Collier and McGuffin: Anxiety and eating disorders13. Liddell, Williams and Owen: The dementiasD - Applications and Implications14. Kerwin and Arranz: Pharmacogenetics15. Scourfield and Owen: Genetic counselling16. Farmer: Ethical considerations17. Owen, McGuffin and Gottesman: The future and post-genomic psychiatry

Editorial Reviews

`This admirable collection provides us with a comprehensive overview of the state-of-the-art of psychiatric genetics and is recommended reading for anyone active or interested in this field.'Genes, Brains and Behaviour