Quantitative Trait Loci: Methods and Protocols by Nicola J. CampQuantitative Trait Loci: Methods and Protocols by Nicola J. Camp

Quantitative Trait Loci: Methods and Protocols

EditorNicola J. Camp, Angela Cox

Paperback | November 10, 2010

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In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.
Title:Quantitative Trait Loci: Methods and ProtocolsFormat:PaperbackDimensions:372 pages, 9.02 × 5.98 × 0 inPublished:November 10, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617372544

ISBN - 13:9781617372544

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Table of Contents

Part I. Mapping Quantitative Trait Loci in HumansAssociation StudiesJennifer H. BarrettParametric Linkage AnalysisLyle J. Palmer, Audrey H. Schnell, John S. Witte, and Robert C. ElstonNonparametric Linkage Analysis: I. Haseman-ElstonChad P. GarnerNonparametric Linkage Analysis: II. Variance ComponentsAngela J. MarlowLinkage and Association: The Transmission/Disequilibrium Test for QTLsMark M. IlesJoint Linkage and Segregation Analysis Using Markov Chain Monte Carlo MethodsEllen M. WijsmanPart II. Mapping Quantitative Trait Loci in RodentsApproaches to the Analysis of QTL Data in Mice, Using the Nonobese Diabetic Mouse as an ExampleHeather J. CordellExperimental Designs for QTL Fine Mapping in RodentsAnne Shalom and Ariel DarvasiApproaches to the Analysis of Complex Quantitative Phenotypes and Marker Map Construction Based on the Analysis of Rat Models of HypertensionDominique Gauguier and Nilesh SamaniA Case Study of QTL Analysis in a Mouse Model of AsthmaYouming Zhang and William CooksonPart III. Mapping Quantitative Trait Loci in Agricultural SettingsQTL Analysis in PlantsShizhong XuQTL Analysis in LivestockJoao L. Rocha, Daniel Pomp, and L. Dale Van VleckIndex

Editorial Reviews

"...for nonstatistical students, this well-designed book provides 'detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results," as advertised on its back cover." - American Journal of Human Biology