Radical-Mediated Protein Oxidation: From Chemistry to Medicine

Hardcover | August 1, 1997

byMichael J. Davies, Roger T. Dean

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Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides,and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of proteinoxidation in human health - including ageing, heart disease, cancer, inflammation and neurodegenerative diseases - and the possible prevention of such processes by antioxidants and other protective strategies.

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Protein oxidation by free radicals is thought to play a major role in many oxidative processes within cells, and is implicated in human disease, carcinogenesis, and ageing. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides,and proteins by free radicals and discusses t...

Professor Roger T. Dean, Director, The Heart Research Institute Ltd, 145-147 Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia. Tel: 0061 2 550 3560. Fax: 0061 2 550 3302. Email: r.dean@hri.edu.au Dr Michael Davies at the same address

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Format:HardcoverDimensions:456 pages, 9.21 × 6.14 × 1.06 inPublished:August 1, 1997Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0198500971

ISBN - 13:9780198500971

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Table of Contents

A historical survey of the study of radical-mediated protein oxidationFormation and chemistry of radicals involved in amino acid, peptide, and protein oxidationThe biochemistry of protein oxidation in cells and cell-free systemsThe physiology of protein oxidationPathology of protein oxidationFuture directions in the study of protein oxidationReferencesIndex

Editorial Reviews

`This is an excellent and long-overdue book...this excellent book should be widely read by everyone in the free radical field. I recommend it highly.'Halliwell, Free Rad.Res,Vol.29