Radiotherapy in practice - radioisotope therapy

Paperback | February 8, 2007

EditorPeter J Hoskin

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Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues. Radioisotope therapyhas an important role to play in modern medicine, particularly in the treatment of thyroid disease, neuroendocrine tumours, bone metastasis and non-Hodgkin's lymphoma. It is found in both the diagnostic setting and in therapy, but recently there has been a renaissance in the application ofradioisotope unsealed sources in therapeutic indications. It is an active area of research, with the quest for new compounds that will be specific for therapeutic targets. This book is an essential, practical guide to the use of radioisotope therapy, and also includes the background and developmental biology which underpins its use. Individual tumours and diseases are explored, with specific focus given to radioisotope treatment options. The barriers to radioisotopetherapy, such as ease of access, acquisition of radioisotopes, radiation protection regulations, and cost are also discussed. ABOUT THE SERIES Radiotherapy remains the major non-surgical treatment modality for the management of malignant disease, with over 50% of patients receiving treatment at some time during the management of their malignant disease. It is based on the application of the principles of applied physics, radiobiology, andtumour biology to clinical practice. Each volume in this series takes the reader through the basic principles of different types of radiotherapy, and then develops these by individual sites. This series of practical handbooks are aimed at physicians both training and practising in radiotherapy, aswell as medical physicists, dosimetrists, radiographers and senior nurses.

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Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues. Radioisotope therapyhas an important role to play in modern med...

Peter Hoskin qualified at the Royal Free Hospital London and trained in Clinical Oncology at the Royal Marsden Hospital. He was appointed consultant at the Royal London Hospital in 1991 and the following year to Mount Vernon Cancer Centre with an academic post in the Department of Oncology at University College London, where he now h...

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Format:PaperbackDimensions:200 pages, 9.13 × 6.14 × 0.67 inPublished:February 8, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198568428

ISBN - 13:9780198568421

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Table of Contents

1. B Pratt and S Evans: Physics principles in the clinical use of radioisotopes2. J L J Dearling and R B Pedley: Antibody directed radioisotope therapy3. Hyer and C Harmer: Radiotherapy for benign thyroid disease: use of I1314. S E M Clarke and U Mallick: Malignant thyroid disease: use of I1315. J Bomanji and G Gnanasegaran: Neuroendocrine tumours6. P Hoskin: Radioisotope therapy for metastatic bone disease7. T Illidge and Y Du: Radioimmunotherapy for lymphoma8. P Hoskin: Other therapeutic use of radioisotopes9. S Evans and B Pratt: Radioprotection and regulatory aspects of radioisotope therapy

Editorial Reviews

"This book is an essential, practical guide to the use of radioisotope therapy, and also includes the background and development biology which underpins its use."--Anticancer Research