Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion…

Hardcover | August 1, 2002

EditorStephen J. Moss, Jeremy Henley

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A volume in the Molecular and Cellular Neurobiology series.This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improvedunderstanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to coverligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors. Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.

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A volume in the Molecular and Cellular Neurobiology series.This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic f...

Stephen Moss is at MRC-LMCB and Department of Pharmacology, University College London, UK. Jeremy Henley is at MRC Centre for Synaptic Plasticity, School of Medical Sciences, University of Bristol, UK.

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Format:HardcoverDimensions:236 pages, 9.45 × 6.61 × 0.72 inPublished:August 1, 2002Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0192632248

ISBN - 13:9780192632241

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Table of Contents

Ion Channels1. Malik-Hall, Wood and Okuse: Voltage-gated sodium channels2. Tinker: The assembly and targeting of potassium channels3. Dolphin: Assembly and targeting of voltage-dependent calcium channelsAcetylcholine Receptors4. Swope: Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse5. Millar: Assembly and targeting of neuronal nicotinic acetylcholine receptorsAmino Acid Receptors6. Stricker and Huganir: AMPA/kainate receptors7. Hering and Sheng: NMDA receptor targeting8. Harvey, von der Nuell and Harvey: Structure, assembly and targeting of glycine receptors9. Luscher: GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover