Receptor Tyrosine Kinases: Family And Subfamilies by Deric L. WheelerReceptor Tyrosine Kinases: Family And Subfamilies by Deric L. Wheeler

Receptor Tyrosine Kinases: Family And Subfamilies

byDeric L. WheelerEditorYosef Yarden

Hardcover | August 13, 2015

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This book devotes a chapter to each RTK family and the multiple receptors within each family, thoroughly covering all of the RTKs. The chapters all follow the same structure, presenting this essential information in an accessible and user-friendly format. Each chapter covers one specific family of receptors and begins with a general introduction to that family and a comprehensive discussion of that receptor's family in development and human disease. Following are in-depth analyses of each family's receptors with discussions on the gene, protein, ligands, activation, and signaling pathways along with discussion of receptor processing and signal attenuation. Further, cross talk with other receptors systems, post-translational modification and specific unique characteristics to each RTK are discussed. Because it isolates and explains each family, this book is an essential companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, by the same authors, which talks about RTKs more generally and without the family-by-family detail.
Dr. Deric Wheeler received an M.S. in pathology from the University of Iowa and a Ph.D. in Cancer Biology from the University of Wisconsin. He conducted his postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle, WA, and at the University of Wisconsin School of Medicine and Public Health in Madison, where he eve...
Title:Receptor Tyrosine Kinases: Family And SubfamiliesFormat:HardcoverDimensions:878 pagesPublished:August 13, 2015Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3319118870

ISBN - 13:9783319118871

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Table of Contents

Anaplastic Lymphoma Kinase (ALK) Receptor Tyrosine Kinase (RTK) Family.- The TAM Receptor Family.-DDR Receptor Tyrosine Kinase Family.- EGFR/ERBB Receptor Tyrosine Kinase Family.- Eph Receptor Tyrosine Kinase Family.- Receptor Tyrosine Kinase textbook - Fibroblast Growth Factor Receptor (FGFR).- Insulin/IGF1 Receptors (INSR/IGF1R) Family.- MET Receptor Tyrosine Kinase Family.- MuSK Receptor Family.- The PDGFR Receptor Family.- PTK7 Receptor Tyrosine Kinase Family.- RET Receptor Tyrosine Kinase.- ROR Receptor Tyrosine Kinase Family.- ROS1 Receptor Tyrosine Kinase.- The RYK Receptor Tyrosine Kinase Subfamily.- TIE Receptor Tyrosine Kinase Family.- TRK Receptor Family.- The VEGF Family of Ligands and Receptors.- NOK Receptor Tyrosine Kinase Family.

Editorial Reviews

"An in depth study of the RTK families in 19 chapters. . Clearly written and with extensive references after each chapter. For endocrinologists, molecular biologists and oncologists." (Pediatric Endocrinology Reviews (PER), Vol. 13 (3), March, 2016)