Receptors: Models for Binding, Trafficking, and Signaling

Paperback | June 1, 1965

byDouglas A. Lauffenburger, Jennifer Linderman

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Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomenainvolving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrumof receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testingand includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such,chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.

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From Our Editors

This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences...

From the Publisher

Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomenainvolving receptor/ligand interactions. In stre...

From the Jacket

This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences...

Douglas A. Lauffenburger is at University of Illinois, Urbana. Jennifer Linderman is at University of Michigan, Ann Arbor.

other books by Douglas A. Lauffenburger

Format:PaperbackDimensions:376 pages, 6.06 × 9.25 × 0.83 inPublished:June 1, 1965Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195106636

ISBN - 13:9780195106633

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Table of Contents

1. Introduction2. Cell Surface Receptor/Ligand Binding Fundamentals3. Receptor/Ligand Trafficking4. Physical Aspects of Receptor/Ligand Binding and Trafficking Processes5. Signal Transduction6. Receptor-Mediated Cell Behavior8. Future Directions

From Our Editors

This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be especially useful.

Editorial Reviews

"[T]his is a book that will become a standard reference in the field." --Journal of Controlled Release