Receptors: structure and function

Paperback | November 15, 2001

EditorClare Stanford, Roger Horton

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Given the number of exciting developments across the whole spectrum of receptor research in recent years, the editors have not restricted themselves to one particular approach or class of receptors. Thus the studies within range from G protein-coupled surface receptors, to the delivery ofantisense DNA inside living cell systems. A distinguished team of contributors cover these diverse areas, identifying any difficulties likely to be encountered and appropriate steps to overcome them.Wherever appropriate, the theoretical basis of each topic is explained first so that the results emerging from the practical procedures can be fully understood. Anyone with an interest in receptor structure and function will find this book an invaluable resource.

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Given the number of exciting developments across the whole spectrum of receptor research in recent years, the editors have not restricted themselves to one particular approach or class of receptors. Thus the studies within range from G protein-coupled surface receptors, to the delivery ofantisense DNA inside living cell systems. A dist...

Clare Stanford is in the Department of Pharmacology, University College London, UK. Roger Horton is in the Department of Pharmacology, St.George's Hospital Medical School, London, UK.
Format:PaperbackDimensions:312 pages, 9.69 × 7.44 × 0.75 inPublished:November 15, 2001Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199638829

ISBN - 13:9780199638826

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Table of Contents

1. Gerardo Turcatti: Probing G protein-coupled receptors by fluorescence spectroscopy2. Hans-Peter Nothacker, Rainer K Reinscheid and Olivier Civelli: From receptor to endogenous ligand3. Dianne M Perez, Michael J Zuscik, Sean A Ross and David J J Waugh: Point mutations and chimeric receptors in studies of ligand binding domains4. F Anne Stephenson and Lynda M Hawkins: Determination of the subunit composition of native and cloned NMDA receptors5. Dmitry M Gakamsky, Richard G Posner and Israel Pecht: Evaluating receptor stoichiometry by fluorescence resonance energy transfer (FRET)6. Raymond Molloy, Antoine Robert, James R Howe and Thomas E Hughes: Monitoring intracellular trafficking of receptors7. J Michael Edwardson: Monitoring the turnover kinetics of G protein-coupled receptors8. Martyn Wood and Darren Smart: Real time receptor function in vitro: microphysiometry and fluorometric imaging plate reader (FLIPR)9. Bernard J McDonald and Richard L Huganir: Regulation of receptors and receptor-coupled ion channels by protein phosphorylation10. Ghassan Bkaily, Danielle Jacques, Pedro d'Orleans-Juste, Ghada Hassan and Sana Choufani: Using confocal imaging to measure changes in intracellular ions11. B Scott Nunez and Wayne V Vedeckis: Monitoring nuclear receptor function12. M Ian Phillips, Keping Qian and Dagmara Mohuczy: In vivo gene transfer of antisense to receptors