Reconstructing Evolution: New Mathematical and Computational Advances

Hardcover | September 12, 2007

EditorOlivier Gascuel, Mike Steel

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Evolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics and sequence evolution is central to comparativegenomics, attempts to decipher genomes, and molecular epidemiology. Phylogenetics is also the focal point of large-scale international biodiversity assessment initiatives such as the 'Tree of Life' project, which aims to build the evolutionary tree for all extant species. Since the pioneering work in phylogenetics in the 1960s, models have become increasingly sophisticated to account for the inherent complexity of evolution. They rely heavily on mathematics and aim at modelling and analyzing biological phenomena such as horizontal gene transfer, heterogeneity ofmutation, and speciation and extinction processes. This book presents these recent models, their biological relevance, their mathematical basis, their properties, and the algorithms to infer them from data. A number of subfields from mathematics and computer science are involved: combinatorics,graph theory, stringology, probabilistic and Markov models, information theory, statistical inference, Monte Carlo methods, continuous and discrete algorithmics. This book arises from the em/Mathematics of Evolution and Phylogenetics/em meeting at the Mathematical Institute Henri Poincare, Paris, in June 2005 and is based on the outstanding state-of-the-art reports presented by the conference speakers. Ten chapters - based around five themes - provide adetailed overview of key topics, from the underlying concepts to the latest results, some of which are at the forefront of current research.

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Evolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics and sequence evolution is central to comparativegenomics, attempts to decipher genomes, and ...

Olivier Gascuel leads a research group at LIRMM-CNRS, Montpellier. He is an associate editor of Systematic Biology and belongs to the editorial board of BMC-Bioinformatics, BMC-Evolutionary Biology, and BMC-Algorithms for Molecular Biology. He has published 110 papers and book chapters, and authored several widely used programs in phy...

other books by Olivier Gascuel

Mathematics of Evolution and Phylogeny
Mathematics of Evolution and Phylogeny

Hardcover|Apr 7 2005

$186.30 online$231.00list price(save 19%)
Format:HardcoverDimensions:352 pages, 9.69 × 6.73 × 0.91 inPublished:September 12, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199208220

ISBN - 13:9780199208227

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Table of Contents

O Gascuel and M Steel: IntroductionList of ContributorsI Evolution in populations1. J Felsenstein: Trees of genes in populations2. A Rodrigo, G Ewing, A Drummond: The evolutionary analysis of measurably evolving populations using serially sampled gene sequencesII Models of sequence evolution3. O Gascuel and S Guindon: Modelling the variability of evolutionary processes4. E Allman and J Rhodes: Phylogenetic invariantsIII Tree shape, speciation and extinction5. A Mooers, L Harmon, M Blum, D Wong, S Heard: Some models of phylogenetic tree shape6. K Hartmann and M Steel: Phylogenetic diversity: from combinatorics to ecologyIV Trees from subtrees and characters7. M Sanderson, C Ane, O Eulenstein, D Fernandez-Baca, J Kim, M McMahon, R Piaggio-Talice: Fragmentation of large data sets in phylogenetic analyses8. S Grunewald and K Huber: Identifying and defining treesV From trees to networks9. D Huson: Split networks and reticulate networks10. C Semple: Hybridization networksIndex