Reviews of Physiology, Biochemistry and Pharmacology 156 by Susan G. AmaraReviews of Physiology, Biochemistry and Pharmacology 156 by Susan G. Amara

Reviews of Physiology, Biochemistry and Pharmacology 156

bySusan G. Amara

Paperback | October 19, 2010

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Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH<_129_20_as20_a20_result20_2b_20_-20_of20_h20_and20_cl20_ion20_secretion20_5b_hydrochloric20_acid20_28_hcl29_20_production5d_20_by20_parietal20_cells20_in20_the20_oxyntic20_mucosa20_of20_the20_stomach.20_the20_combined20_output20_of20_the20_parietal20_cells20_leads20_to20_the20_sec-20_tion20_of20_1-220_l20_of20_hcl20_at20_a20_concentration20_of20_150-16020_mmol2f_l20_into20_the20_interior20_of20_the20_stomach.20_in20_order20_to20_facilitate20_the20_production20_of20_acid2c_20_the20_parietal20_cell20_relies20_on20_the20_generation20_of20_a20_high20_2b_20_concentration20_of20_h20_ions20_that20_are20_transported20_into20_the20_lumen20_of20_the20_gland.20_this20_process20_is20_fa-20_2b_20_2b_20_cilitated20_by20_activation20_of20_the20_gastric20_h20_2c_k20_-atpase2c_20_which20_translocates20_to20_the20_apical20_pole20_of20_2b_20_-20_the20_parietal20_cell.20_k20_as20_well20_as20_atp20_hydrolysis20_and20_cl20_all20_play20_critical20_roles20_in20_the20_activation20_2b_20_2b_20_of20_gastric20_h20_2c_k20_-atpase20_and20_are20_essential20_for20_the20_functioning20_of20_the20_enzyme20_28_reenstra20_and20_forte20_199029_.20_this20_review20_will20_examine20_the20_classical20_proteins20_that20_have20_been20_linked20_to20_acid20_secretion20_as20_well20_as20_some20_recently20_identi3f_ed20_proteins20_that20_may20_modulate20_gastric20_acid20_secretion2c_20_in20_-20_dition20_we20_discuss20_the20_known20_secretagogues2c_20_and20_their20_receptors20_including20_a20_new20_receptor2c_20_which20_upon20_stimulation20_can20_lead20_to20_acid20_secretion. as="" a="" result="" _2b_="" -="" of="" h="" and="" cl="" ion="" secretion="" _5b_hydrochloric="" acid="" _28_hcl29_="" _production5d_="" by="" parietal="" cells="" in="" the="" oxyntic="" mucosa="" stomach.="" combined="" output="" leads="" to="" sec-="" tion="" 1-2="" l="" hcl="" at="" concentration="" 150-160="" _mmol2f_l="" into="" interior="" order="" facilitate="" production="" _acid2c_="" cell="" relies="" on="" generation="" high="" ions="" that="" are="" transported="" lumen="" gland.="" this="" process="" is="" fa-="" cilitated="" activation="" gastric="" _2c_k="" _-atpase2c_="" which="" translocates="" apical="" pole="" cell.="" k="" well="" atp="" hydrolysis="" all="" play="" critical="" roles="" -atpase="" essential="" for="" functioning="" enzyme="" _28_reenstra="" forte="" _199029_.="" review="" will="" examine="" classical="" proteins="" have="" been="" linked="" some="" recently="" _identi3f_ed="" may="" modulate="" _secretion2c_="" dition="" we="" discuss="" known="" _secretagogues2c_="" their="" receptors="" including="" new="" _receptor2c_="" upon="" stimulation="" can="" lead="">
Title:Reviews of Physiology, Biochemistry and Pharmacology 156Format:PaperbackDimensions:90 pages, 23.5 × 15.5 × 0.01 inPublished:October 19, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642068243

ISBN - 13:9783642068249

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Table of Contents

E. A. Craig, P. Huang, R. Aron, and A. Andrew: The diverse roles of J-Proteins, the obligate Hsp70 co-chaperone.- M. Belakavadi and J.D. Fondell: Nuclear hormone receptor signaling.- J.P. Geibel and C. Wagner: An update on acid secretion.- G. Owsianik, D. D'hoedt, T. Voets, and B. Nilius: The TRP channel superfamily.