Reviews of Physiology, Biochemistry and Pharmacology: Special Issue on Cyclic GMP

byG. Schultz, M. P. Blaustein, R. Greger

Paperback | August 23, 2014

Reviews of Physiology, Biochemistry and Pharmacology: Special Issue on Cyclic GMP by G. Schultz
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This special volume provides up-to-date information on research dealing with the regulation of the biosynthesis and degradation of cyclic GMP and with the regulation of physiological systems by cyclic GMP. The publication of this volume could not have come at a more appropriate time, with significant work in this area having led to our current understanding of the role of nitric oxide in signal transduction, and the 1998 Nobel Prize in Medicine and Physiology for Furchgott, Murad and Ignarro.
Moreover, the introduction in early 1998 of sildenafil (Viagra), a selective inhibitor of a cyclic GMP phosphodiesterase, for the treatment of erectile dysfunction in men represents the first successful therapeutic application of an agent designed to alter the activity of a molecular target in a cyclic GMP pathway.
Mechanisms of regulation and functions of guanylyl cyclases.- Soluble guanylyl cyclase: Structure and regulation.- Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs).- Structure and function of cGMP-dependent protein kinases.- Structure and function of cyclic nucleotide-gated channels.- Signal transduc...
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Title:Reviews of Physiology, Biochemistry and Pharmacology: Special Issue on Cyclic GMPFormat:PaperbackProduct dimensions:9.25 X 6.1 X 0 inShipping dimensions:9.25 X 6.1 X 0 inPublished:August 23, 2014Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3662312042

ISBN - 13:9783662312049

Appropriate for ages: All ages

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