Risk Factors for Cerebrovascular Disease and Stroke

Hardcover | March 16, 2016

EditorSudha Seshadri, Stiphanie Debette

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Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental andgenetic determinants for cerebrovascular disease and stroke. The authors aim to provide information on developments of genetic, environmental and lifestyle-related risk factors of various subtypes of stroke, and MRI-markers of cerebrovascular disease.With one in 2 men, and 1 in 3 women after the age of 40, will develop a stroke in their lifetime. The burden of cerebrovascular disease extends far beyond that of acute clinical events such as stroke, with "covert" vascular injury on brain MRI being highly prevalent in older community-dwellingpersons. Therefore, improving our understanding of the risk factors for stroke and cerebrovascular disease is of paramount importance for improving prevention strategies. Secular trends in stroke epidemiology, risk factors, and intermediate markers (including carotid ultrasound, brain MRI andcirculating biomarkers) are presented. Cutting edge information on genetic, environmental and lifestyle-related risk factors of various subtypes of stroke and MRI-markers of cerebrovascular diseases are displayed. This important book is an essential reference to physicians interested in more effective primary prevention of stroke.

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Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental andgenetic determinants for cerebrovascular dis...

Sudha Seshadri, MD, is affiliated with the Department of Neurology at Boston University School of Medicine and is Investigator at The Framingham Heart Study in Boston, MA. Stephanie Debette, MD, PhD, is affiliated with the Department of Neurology and Epidemiology at Paris Diderot University in Paris, France.

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Format:HardcoverDimensions:488 pages, 9.25 × 6.12 × 0.98 inPublished:March 16, 2016Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199895848

ISBN - 13:9780199895847

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Table of Contents

I. Introduction1. Epidemiology of stroke: incidence and prevalence, description of types and subtypes and their relative frequency, definition of risk factorsII. Genetic risk factors2. Introduction to Genetic risk factors for cerebrovascular disease3. Monogenic forms of stroke and cerebrovascular disease4. Heritability of stroke5. Genetic determinants of ischemic stroke discovered through GWAS6. Genetic risk factors of intracerebral haemorrhage7. Relevance in stroke of genes associated with cardiovascular disease and risk factors8. Genetics of Stroke associated with cervical artery dissections9. Genetics of cerebral venous thrombosis10. Genetic risk factors for brain MRI markers of cerebrovascular diseaseIII. Environmental risk factors11. Overview of Environmental Risk Factors for Stroke12. Hypertension: the major risk factor for stroke13. Dyslipidemia and Risk of Stroke14. Metabolic risk factors: DM, obesity, metabolic syndrome15. Lifestyle factors and Risk of Stroke: smoking, alcohol, diet, physical activity, sleep16. Risk factors specific to young adults17. Sex-Specific Risk factors for Stroke in Women18. Migraine and Risk of Stroke and Cerebrovascular Disease19. Ethnic, Racial and Geographic Variations in Stroke Risk and Risk FactorsIV. Integrative approach20. Intermediate markers: Carotid Atherosclerosis21. MRI-based Markers of Cerebrovascular Disease and the Risk of Stroke22. Circulating Biomarkers for Stroke23. Secular trends in Stroke Risk and Risk factors for Stroke