Role of Capsaicin in Oxidative Stress and Cancer by Sanjay K. SrivastavaRole of Capsaicin in Oxidative Stress and Cancer by Sanjay K. Srivastava

Role of Capsaicin in Oxidative Stress and Cancer

bySanjay K. Srivastava

Hardcover | May 7, 2013

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This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
Title:Role of Capsaicin in Oxidative Stress and CancerFormat:HardcoverDimensions:178 pagesPublished:May 7, 2013Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9400763166

ISBN - 13:9789400763166

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Table of Contents

Preface
Chapter 1 Role of capsaicin in cancer prevention
Chapter 2 Role of death receptors belonging to the TNF
family in capsaicin-induced apoptosis of tumor
cells
Chapter 3 Role of capsaicin in prostate cancer
Chapter 4 Capsaicin and the urinary bladder
Chapter 5 Inhibition of pancreatitis and carcinogenesis by
capsaicin
Chapter 6 Cytochrome P450-dependent modification of
capsaicinoids: pharmacological inactivation and
bioactivation mechanisms
Chapter 7 The cancer suppressing and promoting actions of
capsaicin
Chapter 8 Oxidative stress by capsaicin in cancer