Rosenberg's Molecular And Genetic Basis Of Neurological And Psychiatric Disease

Hardcover | November 13, 2014

byRoger N. RosenbergEditorJuan M. Pascual

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Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

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From the Publisher

Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new...

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Rosenberg's Molecular and Genetic Basis of Neurologic and Psychiatric Disease,Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new ...

Roger N. Rosenberg, MD holds the Abe (Brunky), Morris and William Zale Distinguished Chair and Professor of Neurology, University of Texas Southwestern Medical Center at Dallas. He served as Chair of the Department of Neurology from 1973- 1991. He is the founding Director of the NIH funded Alzheimer's Disease Center at UT Southwestern ...

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Format:HardcoverDimensions:1464 pages, 10.88 × 8.5 × 0.98 inPublished:November 13, 2014Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0124105297

ISBN - 13:9780124105294

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Extra Content

Table of Contents

Section I. GENERAL CONCEPTS AND TOOLS

Section II. NEUROLOGIC DISEASES

NEUROMETABOLIC DISORDERS

Mitochondrial Disorders

Lysosomal Disorders

Metal Metabolism Disorders

Vitamin Disorders

Lipid Metabolism Disorders

Other Metabolic Disorders

DEGENERATIVE DISORDERS

MOVEMENT DISORDERS

NEURO-ONCOLOGY

NEUROCUTANEOUS DISORDERS

EPILEPSY

WHITE MATTER DISEASES

NEUROPATHIES AND NEURONOPATHIES

MUSCLE AND NEUROMUSCULAR JUNCTION DISORDERS

STROKE

Section III. PSYCHIATRIC DISEASE

Section IV. A NEUROLOGIC AND PSYCHIATRIC GENE MAP

Editorial Reviews

"...a thoroughly updated, essential book on the genetics of neurological and psychiatric disorders. Every clinician and researcher in neurology and psychiatry ought to be aware of the important information contained in this outstanding book. Score: 91 - 4 Stars"--Doody's, Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease, Fifth Edition Genetics and genomics have changed the practice of neurology and will continue to have huge impact on every discipline of medicine. In this fifth edition of the "bible" of Neurogenetics, Dr. Rosenberg and Dr. Pascual have done a remarkable job in leading the assembly of a volume that is truly representative of this rapidly advancing field -more than ½ of the chapters are new since the last edition. Here, in one place, one can access not only the genetics of common disorders, but virtually every metabolic disorder seen by neurologists, and new chapters on some of the major psychiatric disorders where genetics has played a crucial role in beginning to clarify disease pathophysiology. All of the major disorders, from those afflicting cortex to peripheral muscle are covered by the leading experts in their fields in a clear and authoritative manner. The organization is well conceived and progressive, beginning by providing a conceptual basis for the field, covering basic topics such as genetic counseling, genotype-phenotype relationships, the determination of causality in genetics, and new technologies such as genome sequencing in an exceptionally clear and comprehensive manner. Whether an expert or novice, if you are looking for one book that covers the field from A to Z, this is it. - Daniel Geschwind, Gordon and Virginia MacDonald Distinguished Professor Neurology, Psychiatry and Human Genetics and Director, Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA